Uroinfectio kezelése foszfomycinnel a nogyógyászati gyakorlatban

Translated title of the contribution: Treatment of urinary tract infection using fosfomycin in gynecological practice

József Werling, Tamás Csermely, Péter Kerecsényi, I. Szabó

Research output: Contribution to journalArticle

Abstract

The efficacy of single dose fosfomycin trometamol (if necessary administered repeatedly) was examined in treatment of lower urinary tract infections in 78 women who underwent different gynecological operations. Most common pathogens isolated from urine samples of the patients with posztoperative acut cystitis were Escherichia coli and Enterococci. Two days after 3g single dose oral fosfomycin administration urine samples have became negative in 65 cases (eradication rate 83.3%). In the remaining cases with positive urine culture or with persistent symptoms the patients recieved a second dose of fosfomycin. Urine samples cultured again after two days proved to be positive repeatedly only in 3 cases (total eradication rate 96.1%). All of these have became negative microbiologically and clinically after a third regimen of fosfomycin combined with traditional urodesinfecting agents. The efficacy of fosfomycin in the prophylaxis of cystitis after anterior colporrhaphy was studied in an other, comperative study. Cystitis occured in 33.3% (4/12) in the group treated with single - dose fosfomycin in contrast with 71.4 % (5/7) observed in the group without prophylaxis. Fosfomycin trometamol is an effective, easy to use and well tolerated agent in the treatment of acute cystitis after gynecological operations. It's use is recommended in the prophylaxis of urinary tract infection after colporrhaphy as well.

Original languageHungarian
Pages (from-to)291-296
Number of pages6
JournalMagyar Noorvosok Lapja
Volume67
Issue number5
Publication statusPublished - 2004

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Fosfomycin
Urinary Tract Infections
Cystitis
Urine
Tromethamine
Therapeutics
Enterococcus
Oral Administration
Escherichia coli

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Werling, J., Csermely, T., Kerecsényi, P., & Szabó, I. (2004). Uroinfectio kezelése foszfomycinnel a nogyógyászati gyakorlatban. Magyar Noorvosok Lapja, 67(5), 291-296.

Uroinfectio kezelése foszfomycinnel a nogyógyászati gyakorlatban. / Werling, József; Csermely, Tamás; Kerecsényi, Péter; Szabó, I.

In: Magyar Noorvosok Lapja, Vol. 67, No. 5, 2004, p. 291-296.

Research output: Contribution to journalArticle

Werling, J, Csermely, T, Kerecsényi, P & Szabó, I 2004, 'Uroinfectio kezelése foszfomycinnel a nogyógyászati gyakorlatban', Magyar Noorvosok Lapja, vol. 67, no. 5, pp. 291-296.
Werling, József ; Csermely, Tamás ; Kerecsényi, Péter ; Szabó, I. / Uroinfectio kezelése foszfomycinnel a nogyógyászati gyakorlatban. In: Magyar Noorvosok Lapja. 2004 ; Vol. 67, No. 5. pp. 291-296.
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