Treatment of pigs experimentally infected with Mycoplasma hyopneumoniae, Pasteurella multocida, and Actinobacillus pleuropneumoniae with various antibiotics

L. Stipkovits, D. Miller, R. Glavits, L. Fodor, D. Burch

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The authors have performed a comparative study of the efficacy of various in-feed medications for the treatment of 5- to 6-week-old specific pathogen-free (SPF) piglets experimentally infected on day 1 with Mycoplasma hyopneumoniae, on day 8 with Pasteurella multocida (serotype A), and on day 15 with Actinobacillus pleuropneumoniae (serotype 2). The treatment started on day 9 and continued for 12 consecutive days, then the piglets were euthanized for examination of macroscopic, histologic, and pathologic lesions and for the presence of mycoplasmas and bacteria in the lungs. Based on the results of clinical observations (respiratory signs, rectal temperature, body weight gain, and feed conversion efficiency), macroscopic and histologic lesions of the lungs, and microbiologic findings, the best results were obtained by treatment of pigs with Econor + chlortetracycline, followed by Tetramutin, Pulmotil, Cyfac, and lincomycin + chlortetracycline.

Original languageEnglish
Pages (from-to)213-222
Number of pages10
JournalCanadian Journal of Veterinary Research
Volume65
Issue number4
Publication statusPublished - 2001

Fingerprint

Mycoplasma hyopneumoniae
Actinobacillus pleuropneumoniae
Pasteurella multocida
Chlortetracycline
chlortetracycline
lesions (animal)
piglets
Swine
Actinobacillus pleuropneumoniae 2
antibiotics
lungs
Anti-Bacterial Agents
Lincomycin
Specific Pathogen-Free Organisms
medicated feeds
lincomycin
Lung
swine
Mycoplasma
Weight Gain

ASJC Scopus subject areas

  • veterinary(all)

Cite this

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title = "Treatment of pigs experimentally infected with Mycoplasma hyopneumoniae, Pasteurella multocida, and Actinobacillus pleuropneumoniae with various antibiotics",
abstract = "The authors have performed a comparative study of the efficacy of various in-feed medications for the treatment of 5- to 6-week-old specific pathogen-free (SPF) piglets experimentally infected on day 1 with Mycoplasma hyopneumoniae, on day 8 with Pasteurella multocida (serotype A), and on day 15 with Actinobacillus pleuropneumoniae (serotype 2). The treatment started on day 9 and continued for 12 consecutive days, then the piglets were euthanized for examination of macroscopic, histologic, and pathologic lesions and for the presence of mycoplasmas and bacteria in the lungs. Based on the results of clinical observations (respiratory signs, rectal temperature, body weight gain, and feed conversion efficiency), macroscopic and histologic lesions of the lungs, and microbiologic findings, the best results were obtained by treatment of pigs with Econor + chlortetracycline, followed by Tetramutin, Pulmotil, Cyfac, and lincomycin + chlortetracycline.",
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AU - Miller, D.

AU - Glavits, R.

AU - Fodor, L.

AU - Burch, D.

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