Treatment of chronic pain syndromes with iontophoresis of vinca alkaloids to the skin of patients

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Repeated iontophoretic administration of the microtubule inhibitors vinblastic or vincristine to the segmentally related dermatomes of patients suffering from postherpetic, trigeminal and other neuralgias permanently alleviates chronic, autochthonoue pain. The beneficial effect of this therapy is probably due to transganglionic degenerative atrophy of primary central sensory terminals in the Rolando substance by blockade of retrograde axoplasmic transport in sensory nerves.

Original languageEnglish
Pages (from-to)87-90
Number of pages4
JournalNeuroscience Letters
Volume31
Issue number1
DOIs
Publication statusPublished - Jul 20 1982

Fingerprint

Vinca Alkaloids
Iontophoresis
Axonal Transport
Vincristine
Microtubules
Chronic Pain
Atrophy
Skin
Therapeutics

Keywords

  • iontophoresis
  • pain therapy
  • vinblastine
  • vincristine

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Treatment of chronic pain syndromes with iontophoresis of vinca alkaloids to the skin of patients. / Csillik, B.; Knyihár-Csillik, E.; Szücs, Attila.

In: Neuroscience Letters, Vol. 31, No. 1, 20.07.1982, p. 87-90.

Research output: Contribution to journalArticle

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