Krónikus C-vírus-hepatitis kezelése haemophiliában

Translated title of the contribution: Treatment of chronic hepatitis C in haemophilia patients

Endre Ibrányi, László Nemes

Research output: Contribution to journalArticle


Adults with inherited disorders of coagulation have one of the highest prevalence rates of hepatitis C among known risk groups. Few data are available on the use of combination therapy with interferon and ribavirin in this population. The patients had HCV RNA detectable in serum by polymerase chain reaction, elevated serum aminotransferase (more than 100 U/I). Liver biopsy was not performed. The treatment with interferon alfa 2 b 3 × 3 million units weekly and ribavirin 800 mg/day for 48 weeks. 19 patients were treated and the sustained virological response was 40% (8 of 19). Hemoglobin mean values decreased during treatment, nevertheless all patients were able to finish treatment with small dose adjustments. The re-treatment of 4 nonrespondent patients (interferon and ribavirin) treated again with Peg-interferon alfa 2 b plus ribavirin proved ineffective too.

Translated title of the contributionTreatment of chronic hepatitis C in haemophilia patients
Original languageHungarian
Pages (from-to)61-63
Number of pages3
JournalOrvosi hetilap
Issue number2
Publication statusPublished - Jan 15 2006

ASJC Scopus subject areas

  • Medicine(all)

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