Drug delivery to the central nervous system (CNS) has long been recognised as an enormous task, due to the physiological gate-keeping function of the blood-brain barrier (BBB). With the development of molecular biology, the function and properties of the BBB are better understood. In this review, transporterization, a promising method for drug delivery by endogenous proteins, is discussed, and a survey of the reported results is presented.
|Title of host publication||Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates|
|Publisher||Bentham Science Publishers Ltd.|
|Number of pages||16|
|Publication status||Published - Dec 1 2011|
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)