Transition metal complexes bearing flexible N3 or N3O donor ligands

Reactivity toward superoxide radical anion and hydrogen peroxide

J. Pap, Balázs Kripli, István Bors, Dániel Bogáth, Michel Giorgi, J. Kaizer, G. Speier

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Mononuclear complexes of N-methylpropanoate-N,N-bis-(2-pyridylmethyl)amine (MPBMPA) and N-propanoate-N,N-bis-(2-pyridylmethyl)amine (HPBMPA) with first row transition metals from Mn to Cu were synthesized and characterized by spectroscopy (infrared, UV-visible), electrochemistry (cyclic voltammetry), microanalysis and in four cases X-ray crystallography. Structure of the complexes revealed high flexibility of these ligands that can adopt facial (Fe) and meridional (Cu) geometry. Activity in the degradation of reactive oxygen species (superoxide radical anion: superoxide dismutase (SOD)-like activity and hydrogen peroxide: catalase-like activity) was tested throughout the complex series in aqueous solutions. In connection with the catalytic dismutation of H2O2, bleaching tests with morin were also conducted in water. Comparison of the two ligands helped in elucidating the possible role of the carboxylate moiety in the different catalytic reactions. Although no general trends could be revealed between reactivity and constitution of the first coordination sphere, plausible explanations for differences are discussed individually for SOD like, catalase-like and bleaching activity.

Original languageEnglish
Pages (from-to)60-70
Number of pages11
JournalJournal of Inorganic Biochemistry
Volume117
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Bearings (structural)
Coordination Complexes
Bleaching
Superoxides
Catalase
Hydrogen Peroxide
Superoxide Dismutase
Transition metals
Anions
Ligands
Electrochemistry
X ray crystallography
X Ray Crystallography
Constitution and Bylaws
Propionates
Cyclic voltammetry
Infrared spectroscopy
Reactive Oxygen Species
Spectrum Analysis
Negative ions

Keywords

  • Bleaching
  • Catalase-like activity
  • Morin
  • Redox chemistry
  • SOD-like activity

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry

Cite this

Transition metal complexes bearing flexible N3 or N3O donor ligands : Reactivity toward superoxide radical anion and hydrogen peroxide. / Pap, J.; Kripli, Balázs; Bors, István; Bogáth, Dániel; Giorgi, Michel; Kaizer, J.; Speier, G.

In: Journal of Inorganic Biochemistry, Vol. 117, 12.2012, p. 60-70.

Research output: Contribution to journalArticle

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AU - Kaizer, J.

AU - Speier, G.

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