Transient and sustained expression of FMRFamide-like immunoreactivity in the developing nervous system of Lymnaea stagnalis (Mollusca, Pulmonata)

Elena E. Voronezhskaya, K. Elekes

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

1. In the present study we have investigated the ontogeny of FMRFamide expression in the snail, Lymnaea stagnalis, from its first appearance to its distribution in young adults. 2. The first FMRFamide-like immunoreactive (FaLI) cells within CNS appear by E45 embryonic stage (premetamorphic veliger). The number of FaLI neurons increases throughout both pre- and post- hatching development. 3. Both transient and sustained expression of FMRFamide-like immunoreactivity by specific sets of neurons occurs. Two cells which transiently express immunoreactivity appear outside the future CNS by the stage E45. Other population of transient FaLI neurons includes bilaterally symmetric groups of cells in the cerebral and pedal ganglia during posthatching stages P1 (hatchlings) to P5 (juveniles). All other immunostained cells which appear during development maintain their transmitter phenotype into adulthood. 4. The possible role of FMRFamide- related peptides in the processes of morpho- and neurogenesis is discussed.

Original languageEnglish
Pages (from-to)661-676
Number of pages16
JournalCellular and Molecular Neurobiology
Volume16
Issue number6
DOIs
Publication statusPublished - 1996

Fingerprint

FMRFamide
Lymnaea
Mollusca
Neurology
Nervous System
Neurons
Neurogenesis
Snails
Morphogenesis
Ganglia
Foot
Young Adult
Transmitters
Phenotype
Peptides
Population

Keywords

  • development
  • FMRFamide
  • gastropod
  • immunoreactivity
  • Lymnae a
  • mollusc
  • neuropeptides

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Biochemistry
  • Cell Biology
  • Genetics

Cite this

@article{4b3d2f2f510e411aa633445833b8820d,
title = "Transient and sustained expression of FMRFamide-like immunoreactivity in the developing nervous system of Lymnaea stagnalis (Mollusca, Pulmonata)",
abstract = "1. In the present study we have investigated the ontogeny of FMRFamide expression in the snail, Lymnaea stagnalis, from its first appearance to its distribution in young adults. 2. The first FMRFamide-like immunoreactive (FaLI) cells within CNS appear by E45 embryonic stage (premetamorphic veliger). The number of FaLI neurons increases throughout both pre- and post- hatching development. 3. Both transient and sustained expression of FMRFamide-like immunoreactivity by specific sets of neurons occurs. Two cells which transiently express immunoreactivity appear outside the future CNS by the stage E45. Other population of transient FaLI neurons includes bilaterally symmetric groups of cells in the cerebral and pedal ganglia during posthatching stages P1 (hatchlings) to P5 (juveniles). All other immunostained cells which appear during development maintain their transmitter phenotype into adulthood. 4. The possible role of FMRFamide- related peptides in the processes of morpho- and neurogenesis is discussed.",
keywords = "development, FMRFamide, gastropod, immunoreactivity, Lymnae a, mollusc, neuropeptides",
author = "Voronezhskaya, {Elena E.} and K. Elekes",
year = "1996",
doi = "10.1007/BF02151903",
language = "English",
volume = "16",
pages = "661--676",
journal = "Cellular and Molecular Neurobiology",
issn = "0272-4340",
publisher = "Springer New York",
number = "6",

}

TY - JOUR

T1 - Transient and sustained expression of FMRFamide-like immunoreactivity in the developing nervous system of Lymnaea stagnalis (Mollusca, Pulmonata)

AU - Voronezhskaya, Elena E.

AU - Elekes, K.

PY - 1996

Y1 - 1996

N2 - 1. In the present study we have investigated the ontogeny of FMRFamide expression in the snail, Lymnaea stagnalis, from its first appearance to its distribution in young adults. 2. The first FMRFamide-like immunoreactive (FaLI) cells within CNS appear by E45 embryonic stage (premetamorphic veliger). The number of FaLI neurons increases throughout both pre- and post- hatching development. 3. Both transient and sustained expression of FMRFamide-like immunoreactivity by specific sets of neurons occurs. Two cells which transiently express immunoreactivity appear outside the future CNS by the stage E45. Other population of transient FaLI neurons includes bilaterally symmetric groups of cells in the cerebral and pedal ganglia during posthatching stages P1 (hatchlings) to P5 (juveniles). All other immunostained cells which appear during development maintain their transmitter phenotype into adulthood. 4. The possible role of FMRFamide- related peptides in the processes of morpho- and neurogenesis is discussed.

AB - 1. In the present study we have investigated the ontogeny of FMRFamide expression in the snail, Lymnaea stagnalis, from its first appearance to its distribution in young adults. 2. The first FMRFamide-like immunoreactive (FaLI) cells within CNS appear by E45 embryonic stage (premetamorphic veliger). The number of FaLI neurons increases throughout both pre- and post- hatching development. 3. Both transient and sustained expression of FMRFamide-like immunoreactivity by specific sets of neurons occurs. Two cells which transiently express immunoreactivity appear outside the future CNS by the stage E45. Other population of transient FaLI neurons includes bilaterally symmetric groups of cells in the cerebral and pedal ganglia during posthatching stages P1 (hatchlings) to P5 (juveniles). All other immunostained cells which appear during development maintain their transmitter phenotype into adulthood. 4. The possible role of FMRFamide- related peptides in the processes of morpho- and neurogenesis is discussed.

KW - development

KW - FMRFamide

KW - gastropod

KW - immunoreactivity

KW - Lymnae a

KW - mollusc

KW - neuropeptides

UR - http://www.scopus.com/inward/record.url?scp=0030464573&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030464573&partnerID=8YFLogxK

U2 - 10.1007/BF02151903

DO - 10.1007/BF02151903

M3 - Article

C2 - 9013029

AN - SCOPUS:0030464573

VL - 16

SP - 661

EP - 676

JO - Cellular and Molecular Neurobiology

JF - Cellular and Molecular Neurobiology

SN - 0272-4340

IS - 6

ER -