Transgenerational endocrine disruption: Does elemental pollution affect egg or nestling thyroid hormone levels in a wild songbird?

Suvi Ruuskanen, Silvia Espín, Pablo Sánchez-Virosta, Tom Sarraude, Bin Yan Hsu, Piia Pajunen, Rute A. Costa, Marcel Eens, R. Hargitai, J. Török, Tapio Eeva

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Endocrine disrupting chemicals (EDCs) include a wide array of pollutants, such as some metals and other toxic elements, which may cause changes in hormonal homeostasis. In addition to affecting physiology of individuals directly, EDCs may alter the transfer of maternal hormones to offspring, i.e. causing transgenerational endocrine disruption. However, such effects have been rarely studied, especially in wild populations. We studied the associations between environmental elemental pollution (As, Cd, Cu, Ni, Pb) and maternally-derived egg thyroid hormones (THs) as well as nestling THs in great tits (Parus major) using extensive sampling of four pairs of polluted and reference populations across Europe (Finland, Belgium, Hungary, Portugal). Previous studies in these populations showed that breeding success, nestling growth and adult and nestling physiology were altered in polluted zones compared to reference zones. We sampled non-incubated eggs to measure maternally-derived egg THs, measured nestling plasma THs and used nestling faeces for assessing local elemental exposure. We also studied whether the effect of elemental pollution on endocrine traits is dependent on calcium (Ca) availability (faecal Ca as a proxy) as low Ca increases toxicity of some elements. Birds in the polluted zones were exposed to markedly higher levels of toxic elements than in reference zones at the populations in Finland, Belgium and Hungary. In contrast to our predictions, we did not find any associations between overall elemental pollution, or individual element concentrations and egg TH and nestling plasma TH levels. However, we found some indication that the effect of metals (Cd and Cu) on egg THs is dependent on Ca availability. In summary, our results suggest that elemental pollution at the studied populations is unlikely to cause overall TH disruption and affect breeding via altered egg or nestling TH levels with the current elemental pollution loads. Associations with Ca availability should be further studied.

Original languageEnglish
Pages (from-to)725-735
Number of pages11
JournalEnvironmental Pollution
Volume247
DOIs
Publication statusPublished - Apr 1 2019

Fingerprint

Songbirds
Thyroid Hormones
Ovum
Pollution
Calcium
Endocrine Disruptors
Hungary
Population
Poisons
Belgium
Physiology
Availability
Finland
Breeding
Metals
Plasmas
Environmental Pollution
Portugal
Hormones
Birds

Keywords

  • Elemental pollution
  • Endocrine disruption
  • Great tits
  • Prohormone thyroxine
  • Transgenerational effects
  • Tri-iodothyronine
  • Wild bird populations

ASJC Scopus subject areas

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

Transgenerational endocrine disruption : Does elemental pollution affect egg or nestling thyroid hormone levels in a wild songbird? / Ruuskanen, Suvi; Espín, Silvia; Sánchez-Virosta, Pablo; Sarraude, Tom; Hsu, Bin Yan; Pajunen, Piia; Costa, Rute A.; Eens, Marcel; Hargitai, R.; Török, J.; Eeva, Tapio.

In: Environmental Pollution, Vol. 247, 01.04.2019, p. 725-735.

Research output: Contribution to journalArticle

Ruuskanen, Suvi ; Espín, Silvia ; Sánchez-Virosta, Pablo ; Sarraude, Tom ; Hsu, Bin Yan ; Pajunen, Piia ; Costa, Rute A. ; Eens, Marcel ; Hargitai, R. ; Török, J. ; Eeva, Tapio. / Transgenerational endocrine disruption : Does elemental pollution affect egg or nestling thyroid hormone levels in a wild songbird?. In: Environmental Pollution. 2019 ; Vol. 247. pp. 725-735.
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