Transformation of compounds containing C-N bonds on heterogeneous catalysis. Part IV1 1 For Part in, see [1].. Hydrogenolysis of β lactams on raney ni

a new method for the preparation of 1,3-aminoalcohols

M. Bartók, Lajos Gera, György Göndös, Árpád Molnár

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The transformations of the condensed-skeleton β-lactams (azetidin-2-ones) 1 - 4 were studied under various reductive conditions. On the action of a complex metal hydride, selective formation of azetidines occurs. A new heterogeneous catalytic method is reported, which is suitable for the preparation of cyclic 1,3-aminoalcohols in the presence of Raney Ni in liquid-phase hydrogénation. On a Ni on Cab-O-Sil® catalyst in a flow reactor, 1 is converted to the carboxylic acid amide 9 with high selectivity.

Original languageEnglish
Pages (from-to)103-111
Number of pages9
JournalJournal of Molecular Catalysis
Volume49
Issue number1
DOIs
Publication statusPublished - Dec 15 1988

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Hydrogenolysis
Metal complexes
Carboxylic acids
Amides
Hydrides
Catalysis
Catalysts
Liquids
Lactams

ASJC Scopus subject areas

  • Engineering(all)

Cite this

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abstract = "The transformations of the condensed-skeleton β-lactams (azetidin-2-ones) 1 - 4 were studied under various reductive conditions. On the action of a complex metal hydride, selective formation of azetidines occurs. A new heterogeneous catalytic method is reported, which is suitable for the preparation of cyclic 1,3-aminoalcohols in the presence of Raney Ni in liquid-phase hydrog{\'e}nation. On a Ni on Cab-O-Sil{\circledR} catalyst in a flow reactor, 1 is converted to the carboxylic acid amide 9 with high selectivity.",
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T1 - Transformation of compounds containing C-N bonds on heterogeneous catalysis. Part IV1 1 For Part in, see [1].. Hydrogenolysis of β lactams on raney ni

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AU - Bartók, M.

AU - Gera, Lajos

AU - Göndös, György

AU - Molnár, Árpád

PY - 1988/12/15

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