Chronic lymphocytic leukaemia (CLL) may transform to either malignant lymphoid disorder or increase the occurence of solid neoplasms. However myeloid malignancies seldom develop. We report a case of a patient who has remained untreated for CLL and developed myelodysplastic syndrome (refracter anemia with ringed sideroblasts) six years after the diagnosis of CLL. Development of myelodysplastic syndrome resulted in concurrent attenuation of CLL. Discussion of the pathogenesis of myeloid disorders occuring with CLL and review of the literature are alo presented.
|Translated title of the contribution||Transformation of chronic lymphocytic leukemia to myelodysplastic syndrome: Case presentation and review of the literature|
|Number of pages||4|
|Publication status||Published - Apr 1 2009|
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