Trans-adenosine 3',5'-cyclic N,N-dimethylphosphoramidate ether solvate, a cyclic nucleotide with an equatorial dimethylamino group on phosphorus

Sándor Bottka, Jeno Tomasz, W. B.T. Cruse, Shude Zhang, Olga Kennard

Research output: Contribution to journalArticle

2 Citations (Scopus)


Trans-Adenosine 3',5'-cyclic N,N-dimethylphosphoramidate ether solvate crystallizes as monoclinic prisms elongated about the b-axis. The dioxaphosphorinane ring adopts a flattened chair conformation with an almost planar dimethylamino substituent equatorial. The purine ring conformation is anti. The ribose ring exists in a 3T4 conformation.

Original languageEnglish
Pages (from-to)2123-2131
Number of pages9
JournalNucleosides and Nucleotides
Issue number12
Publication statusPublished - Jan 1 1997


ASJC Scopus subject areas

  • Biochemistry
  • Genetics

Cite this