Towards Properly Controlled Analytical Measurement Methods

K. M. Hangos, L. Leisztner

Research output: Contribution to journalArticle


It is of great practical importance to develop simple methods for the automatic detection of the controlled state of the analytical method being applied. The key point is to find quantities that greatly affect the quality оf the analytical results and that can be easily estimated during the measurement process from the measured data. The signal-to-noise ratio has proved to be such a quantity in gas chromatographic methods. The statistical properties of the estimation of the signal-to-noise ratio from gas chromatographic data have been investigated. The suggested practical method for estimating the signal-to-noise ratio proved to be biased from a mathematical statistical point of view, but the bias is usually not greater than 10%. It has been shown by practical examples that the signal-to-noise ratio affects the quality of the analytical results and it is easy to estimate its value from practical data.

Original languageEnglish
Pages (from-to)76-79
Number of pages4
JournalJournal of Automatic Chemistry
Issue number2
Publication statusPublished - Jan 1 1989


ASJC Scopus subject areas

  • Clinical Biochemistry

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