Topography of orientation centre connections in the primary visual cortex of the cat

Tagrid Yousef, Éva Tóth, Martin Rausch, Ulf T. Eysel, Z. Kisvárday

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The functional topography of lateral connections to orientation-centre zones was studied by optical imaging of intrinsic signals in combination with tracer injections (fluorescent beads and biocytin) and electrophysiological recordings. Three-dimensional reconstruction of anterogradely labelled axon terminals and retrogradely labelled somata revealed a uniform distribution across all orientations in a non-patchy manner. The overall lateral extent of the labelling was 3-4 mm in layer 3, that is about half of the extent observed for orientation domain connections in the same layer. These bulk injection data are in contrast with the reportedly sharp orientation tuning of neurons of centre zones and suggest that orientation specificity here does not require highly specific connections. Nonetheless, another plausible scenario is that orientation centre connections are orientation specific but their specificity present at the single cell level cannot be revealed by bulk labelling due to their large spatial overlap.

Original languageEnglish
Pages (from-to)1693-1699
Number of pages7
JournalNeuroReport
Volume12
Issue number8
Publication statusPublished - Jun 13 2001

Fingerprint

Visual Cortex
Cats
Injections
Optical Imaging
Presynaptic Terminals
Carisoprodol
Neurons
biocytin

Keywords

  • Lateral connections
  • Orientation selectivity
  • Visuotopy

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Yousef, T., Tóth, É., Rausch, M., Eysel, U. T., & Kisvárday, Z. (2001). Topography of orientation centre connections in the primary visual cortex of the cat. NeuroReport, 12(8), 1693-1699.

Topography of orientation centre connections in the primary visual cortex of the cat. / Yousef, Tagrid; Tóth, Éva; Rausch, Martin; Eysel, Ulf T.; Kisvárday, Z.

In: NeuroReport, Vol. 12, No. 8, 13.06.2001, p. 1693-1699.

Research output: Contribution to journalArticle

Yousef, T, Tóth, É, Rausch, M, Eysel, UT & Kisvárday, Z 2001, 'Topography of orientation centre connections in the primary visual cortex of the cat', NeuroReport, vol. 12, no. 8, pp. 1693-1699.
Yousef, Tagrid ; Tóth, Éva ; Rausch, Martin ; Eysel, Ulf T. ; Kisvárday, Z. / Topography of orientation centre connections in the primary visual cortex of the cat. In: NeuroReport. 2001 ; Vol. 12, No. 8. pp. 1693-1699.
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