Topography of chemically identified neurons in the central nervous system: A review

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Data published till the beginning of 1978 on the topography of chemically identified neurons are reviewed. Exclusively the direct immunohistological (immunofluorescence, immunocytochemistry) and neurochemical (radioimmunoassay, enzyme isotopic assay, mass spectrometry, high pressure liquid chromatography) techniques and results are surveyed. The localization of chemically identified cell bodies, axons and termination areas are described and correlated with the biochemically determined concentrations of the substances studied. An attempt is made to define chemical localization patterns in terms of classical neuroanatomy. The distribution of more than 20 chemically, verified substances synthetized by neurons are considered. These comprise the putative neurotransmitters (dopamine, noradrenaline, adrenaline, acetylcholine, GABA), neuronal peptides (substance P, neurotensin, lipotropins, endorphins, enkephalins, VIP) and neurohormone-like substances (LH-RH, TRH, somatostatin, CRF, α-MSH, ACTH, vasopressin, oxytocin neurophysins). Current knowledge of the topochemistry of the above substances is briefly discussed.

Original languageEnglish
Pages (from-to)211-290
Number of pages80
JournalActa Morphologica Academiae Scientiarum Hungaricae
Volume26
Issue number3-4
Publication statusPublished - 1978

Fingerprint

Neurotransmitter Agents
Central Nervous System
beta-Lipotropin
Neurophysins
Endorphins
Melanocyte-Stimulating Hormones
Neurons
Neuroanatomy
Direct Fluorescent Antibody Technique
Neurotensin
Enkephalins
Corticotropin-Releasing Hormone
Enzyme Assays
Oxytocin
Substance P
Somatostatin
Vasopressins
Gonadotropin-Releasing Hormone
gamma-Aminobutyric Acid
Epinephrine

ASJC Scopus subject areas

  • Anatomy

Cite this

@article{c33ed72db2174265a292edf981bac9db,
title = "Topography of chemically identified neurons in the central nervous system: A review",
abstract = "Data published till the beginning of 1978 on the topography of chemically identified neurons are reviewed. Exclusively the direct immunohistological (immunofluorescence, immunocytochemistry) and neurochemical (radioimmunoassay, enzyme isotopic assay, mass spectrometry, high pressure liquid chromatography) techniques and results are surveyed. The localization of chemically identified cell bodies, axons and termination areas are described and correlated with the biochemically determined concentrations of the substances studied. An attempt is made to define chemical localization patterns in terms of classical neuroanatomy. The distribution of more than 20 chemically, verified substances synthetized by neurons are considered. These comprise the putative neurotransmitters (dopamine, noradrenaline, adrenaline, acetylcholine, GABA), neuronal peptides (substance P, neurotensin, lipotropins, endorphins, enkephalins, VIP) and neurohormone-like substances (LH-RH, TRH, somatostatin, CRF, α-MSH, ACTH, vasopressin, oxytocin neurophysins). Current knowledge of the topochemistry of the above substances is briefly discussed.",
author = "M. Palk{\'o}vits",
year = "1978",
language = "English",
volume = "26",
pages = "211--290",
journal = "Acta Morphologica Academiae Scientiarum Hungaricae",
issn = "0001-6217",
publisher = "Akademiai Kiado",
number = "3-4",

}

TY - JOUR

T1 - Topography of chemically identified neurons in the central nervous system

T2 - A review

AU - Palkóvits, M.

PY - 1978

Y1 - 1978

N2 - Data published till the beginning of 1978 on the topography of chemically identified neurons are reviewed. Exclusively the direct immunohistological (immunofluorescence, immunocytochemistry) and neurochemical (radioimmunoassay, enzyme isotopic assay, mass spectrometry, high pressure liquid chromatography) techniques and results are surveyed. The localization of chemically identified cell bodies, axons and termination areas are described and correlated with the biochemically determined concentrations of the substances studied. An attempt is made to define chemical localization patterns in terms of classical neuroanatomy. The distribution of more than 20 chemically, verified substances synthetized by neurons are considered. These comprise the putative neurotransmitters (dopamine, noradrenaline, adrenaline, acetylcholine, GABA), neuronal peptides (substance P, neurotensin, lipotropins, endorphins, enkephalins, VIP) and neurohormone-like substances (LH-RH, TRH, somatostatin, CRF, α-MSH, ACTH, vasopressin, oxytocin neurophysins). Current knowledge of the topochemistry of the above substances is briefly discussed.

AB - Data published till the beginning of 1978 on the topography of chemically identified neurons are reviewed. Exclusively the direct immunohistological (immunofluorescence, immunocytochemistry) and neurochemical (radioimmunoassay, enzyme isotopic assay, mass spectrometry, high pressure liquid chromatography) techniques and results are surveyed. The localization of chemically identified cell bodies, axons and termination areas are described and correlated with the biochemically determined concentrations of the substances studied. An attempt is made to define chemical localization patterns in terms of classical neuroanatomy. The distribution of more than 20 chemically, verified substances synthetized by neurons are considered. These comprise the putative neurotransmitters (dopamine, noradrenaline, adrenaline, acetylcholine, GABA), neuronal peptides (substance P, neurotensin, lipotropins, endorphins, enkephalins, VIP) and neurohormone-like substances (LH-RH, TRH, somatostatin, CRF, α-MSH, ACTH, vasopressin, oxytocin neurophysins). Current knowledge of the topochemistry of the above substances is briefly discussed.

UR - http://www.scopus.com/inward/record.url?scp=0018238951&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018238951&partnerID=8YFLogxK

M3 - Article

C2 - 38636

AN - SCOPUS:0018238951

VL - 26

SP - 211

EP - 290

JO - Acta Morphologica Academiae Scientiarum Hungaricae

JF - Acta Morphologica Academiae Scientiarum Hungaricae

SN - 0001-6217

IS - 3-4

ER -