Topographical regulation of cone and rod opsin genes: parallel, position dependent levels of transcription

Paul R. van Ginkel, Adrian M. Timmers, A. Szél, William W. Hauswirth

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

RNase protection assays were used to follow rhodopsin and red cone opsin mRNA levels during bovine fetal development as a function of retinal position. Following induction, an equivalent radial gradient of rod and cone opsin mRNA is present in the fetal retina. This gradient is maintained in the adult retina even though no corresponding gradient in rod or cone cell density is present. Since the mRNA expression gradient does not progress radially, position dependent levels of photoreceptor-specific transcription is suggested.

Original languageEnglish
Pages (from-to)146-149
Number of pages4
JournalDevelopmental Brain Research
Volume89
Issue number1
DOIs
Publication statusPublished - Oct 27 1995

Fingerprint

Rod Opsins
Cone Opsins
Gene Order
Vertebrate Photoreceptor Cells
Messenger RNA
Retina
Rhodopsin
Ribonucleases
Fetal Development
Cell Count

Keywords

  • Cone opsin mRNA
  • Development
  • Fetal bovine retina
  • Rhodopsin mRNA
  • Topographic gene expression

ASJC Scopus subject areas

  • Developmental Biology
  • Developmental Neuroscience

Cite this

Topographical regulation of cone and rod opsin genes : parallel, position dependent levels of transcription. / van Ginkel, Paul R.; Timmers, Adrian M.; Szél, A.; Hauswirth, William W.

In: Developmental Brain Research, Vol. 89, No. 1, 27.10.1995, p. 146-149.

Research output: Contribution to journalArticle

van Ginkel, Paul R. ; Timmers, Adrian M. ; Szél, A. ; Hauswirth, William W. / Topographical regulation of cone and rod opsin genes : parallel, position dependent levels of transcription. In: Developmental Brain Research. 1995 ; Vol. 89, No. 1. pp. 146-149.
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