Toll-like receptors link atopic march to the hygiene hypothesis

L. Kemény, Kornélia Szabó

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In recent decades, the prevalence of atopic diseases has increased substantially worldwide, but their molecular pathologies are now being elucidated. The report by Haapakoski et al. in this issue suggests that the manner in which the immune system encounters an allergen is key to the subsequent polarization of its responses, and the presence of microbial ligands appears to be important in this process. Data in this report provide further proof of the hygiene hypothesis that combine it with known features of the atopic march.

Original languageEnglish
Pages (from-to)874-878
Number of pages5
JournalJournal of Investigative Dermatology
Volume133
Issue number4
DOIs
Publication statusPublished - Apr 2013

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Hygiene Hypothesis
Molecular Pathology
Immune system
Toll-Like Receptors
Pathology
Allergens
Immune System
Polarization
Ligands

ASJC Scopus subject areas

  • Dermatology
  • Biochemistry
  • Cell Biology
  • Molecular Biology

Cite this

Toll-like receptors link atopic march to the hygiene hypothesis. / Kemény, L.; Szabó, Kornélia.

In: Journal of Investigative Dermatology, Vol. 133, No. 4, 04.2013, p. 874-878.

Research output: Contribution to journalArticle

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