Titania nanofibers in gypsum composites

An antibacterial and cytotoxicology study

Melinda Mohl, Aron Dombovari, Elena S. Tuchina, Pavel O. Petrov, Olga A. Bibikova, Ilya Skovorodkin, Alexey P. Popov, Anne Riikka Rautio, Anjana Sarkar, Jyri Pekka Mikkola, Mika Huuhtanen, Seppo Vainio, Riitta L. Keiski, Arthur Prilepsky, Á. Kukovecz, Z. Kónya, Valery V. Tuchin, Krisztian Kordas

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Further developments of antibacterial coatings based on photocatalytic nanomaterials could be a promising route towards potential environmentally friendly applications in households, public buildings and health care facilities. Hereby we describe a simple chemical approach to synthesize photocatalytic nanomaterial-embedded coatings using gypsum as a binder. Various types of TiO2 nanofiber-based photocatalytic materials (nitrogen-doped and/or palladium nanoparticle decorated) and their composites with gypsum were characterized by means of scanning (SEM) and transmission (TEM) electron microscopy as well as electron and X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX) techniques. These gypsum-based composites can be directly applied as commercially available paints on indoor walls. Herein we report that surfaces coated with photocatalytic composites exhibit excellent antimicrobial properties by killing both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) under blue light. In the case of MSSA cells, the palladium nanoparticle-decorated and nitrogen-doped TiO2 composites demonstrated the highest antimicrobial activity. For the MRSA strain even pure gypsum samples were proven to be efficient in eradicating Gram-positive human pathogens. The cytotoxicity of freestanding TiO2 nanofibers was revealed by analyzing the viability of HeLa cells using MTT and fluorescent cell assays.

Original languageEnglish
Pages (from-to)1307-1316
Number of pages10
JournalJournal of Materials Chemistry B
Volume2
Issue number10
DOIs
Publication statusPublished - Mar 14 2014

Fingerprint

Nanofibers
Calcium Sulfate
Methicillin
Gypsum
Titanium
Nanostructures
Composite materials
Palladium
Methicillin-Resistant Staphylococcus aureus
Nanostructured materials
Nanoparticles
Staphylococcus aureus
Nitrogen
X-Ray Emission Spectrometry
Coatings
Paint
Health Facilities
Pathogens
Cytotoxicity
Transmission Electron Microscopy

ASJC Scopus subject areas

  • Chemistry(all)
  • Biomedical Engineering
  • Medicine(all)
  • Materials Science(all)

Cite this

Mohl, M., Dombovari, A., Tuchina, E. S., Petrov, P. O., Bibikova, O. A., Skovorodkin, I., ... Kordas, K. (2014). Titania nanofibers in gypsum composites: An antibacterial and cytotoxicology study. Journal of Materials Chemistry B, 2(10), 1307-1316. https://doi.org/10.1039/c3tb21644f

Titania nanofibers in gypsum composites : An antibacterial and cytotoxicology study. / Mohl, Melinda; Dombovari, Aron; Tuchina, Elena S.; Petrov, Pavel O.; Bibikova, Olga A.; Skovorodkin, Ilya; Popov, Alexey P.; Rautio, Anne Riikka; Sarkar, Anjana; Mikkola, Jyri Pekka; Huuhtanen, Mika; Vainio, Seppo; Keiski, Riitta L.; Prilepsky, Arthur; Kukovecz, Á.; Kónya, Z.; Tuchin, Valery V.; Kordas, Krisztian.

In: Journal of Materials Chemistry B, Vol. 2, No. 10, 14.03.2014, p. 1307-1316.

Research output: Contribution to journalArticle

Mohl, M, Dombovari, A, Tuchina, ES, Petrov, PO, Bibikova, OA, Skovorodkin, I, Popov, AP, Rautio, AR, Sarkar, A, Mikkola, JP, Huuhtanen, M, Vainio, S, Keiski, RL, Prilepsky, A, Kukovecz, Á, Kónya, Z, Tuchin, VV & Kordas, K 2014, 'Titania nanofibers in gypsum composites: An antibacterial and cytotoxicology study', Journal of Materials Chemistry B, vol. 2, no. 10, pp. 1307-1316. https://doi.org/10.1039/c3tb21644f
Mohl M, Dombovari A, Tuchina ES, Petrov PO, Bibikova OA, Skovorodkin I et al. Titania nanofibers in gypsum composites: An antibacterial and cytotoxicology study. Journal of Materials Chemistry B. 2014 Mar 14;2(10):1307-1316. https://doi.org/10.1039/c3tb21644f
Mohl, Melinda ; Dombovari, Aron ; Tuchina, Elena S. ; Petrov, Pavel O. ; Bibikova, Olga A. ; Skovorodkin, Ilya ; Popov, Alexey P. ; Rautio, Anne Riikka ; Sarkar, Anjana ; Mikkola, Jyri Pekka ; Huuhtanen, Mika ; Vainio, Seppo ; Keiski, Riitta L. ; Prilepsky, Arthur ; Kukovecz, Á. ; Kónya, Z. ; Tuchin, Valery V. ; Kordas, Krisztian. / Titania nanofibers in gypsum composites : An antibacterial and cytotoxicology study. In: Journal of Materials Chemistry B. 2014 ; Vol. 2, No. 10. pp. 1307-1316.
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