Thyroxine and triiodothyronine uptake by the brain of chickens.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The instant uptake of 125-I-labelled triiodothyronine and 125-I-thyroxine by the brain tissue was measured in sham-operated (SH) controls, thyroidectomized (TX) and thyroidectomized plus iodothyronine supplemented (TX+T3 or TX+T4) young chickens. It was found that thyroidectomy significantly increases the uptake of iodothyronines, and iodothyronine supplementation returns the uptake close to sham-operated levels. The characteristics of the inhibition of the uptake of labelled hormones by non-labelled iodothyronines speak in favour of the presence of specific, separate uptake sites for T3 and T4 in the blood-brain barrier of young chickens.

Original languageEnglish
Pages (from-to)395-408
Number of pages14
JournalActa Veterinaria Hungarica
Volume41
Issue number3-4
Publication statusPublished - 1993

Fingerprint

Triiodothyronine
triiodothyronine
thyroxine
Thyroxine
Chickens
chickens
uptake mechanisms
brain
Thyroidectomy
Brain
Blood-Brain Barrier
L-thyroxine
Hormones
blood-brain barrier
hormones

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Thyroxine and triiodothyronine uptake by the brain of chickens. / Rudas, P.; Bartha, T.

In: Acta Veterinaria Hungarica, Vol. 41, No. 3-4, 1993, p. 395-408.

Research output: Contribution to journalArticle

@article{96c58ca9c8d84daa9f78834ec5137c43,
title = "Thyroxine and triiodothyronine uptake by the brain of chickens.",
abstract = "The instant uptake of 125-I-labelled triiodothyronine and 125-I-thyroxine by the brain tissue was measured in sham-operated (SH) controls, thyroidectomized (TX) and thyroidectomized plus iodothyronine supplemented (TX+T3 or TX+T4) young chickens. It was found that thyroidectomy significantly increases the uptake of iodothyronines, and iodothyronine supplementation returns the uptake close to sham-operated levels. The characteristics of the inhibition of the uptake of labelled hormones by non-labelled iodothyronines speak in favour of the presence of specific, separate uptake sites for T3 and T4 in the blood-brain barrier of young chickens.",
author = "P. Rudas and T. Bartha",
year = "1993",
language = "English",
volume = "41",
pages = "395--408",
journal = "Acta Veterinaria Hungarica",
issn = "0236-6290",
publisher = "Akademiai Kiado",
number = "3-4",

}

TY - JOUR

T1 - Thyroxine and triiodothyronine uptake by the brain of chickens.

AU - Rudas, P.

AU - Bartha, T.

PY - 1993

Y1 - 1993

N2 - The instant uptake of 125-I-labelled triiodothyronine and 125-I-thyroxine by the brain tissue was measured in sham-operated (SH) controls, thyroidectomized (TX) and thyroidectomized plus iodothyronine supplemented (TX+T3 or TX+T4) young chickens. It was found that thyroidectomy significantly increases the uptake of iodothyronines, and iodothyronine supplementation returns the uptake close to sham-operated levels. The characteristics of the inhibition of the uptake of labelled hormones by non-labelled iodothyronines speak in favour of the presence of specific, separate uptake sites for T3 and T4 in the blood-brain barrier of young chickens.

AB - The instant uptake of 125-I-labelled triiodothyronine and 125-I-thyroxine by the brain tissue was measured in sham-operated (SH) controls, thyroidectomized (TX) and thyroidectomized plus iodothyronine supplemented (TX+T3 or TX+T4) young chickens. It was found that thyroidectomy significantly increases the uptake of iodothyronines, and iodothyronine supplementation returns the uptake close to sham-operated levels. The characteristics of the inhibition of the uptake of labelled hormones by non-labelled iodothyronines speak in favour of the presence of specific, separate uptake sites for T3 and T4 in the blood-brain barrier of young chickens.

UR - http://www.scopus.com/inward/record.url?scp=0027791950&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027791950&partnerID=8YFLogxK

M3 - Article

VL - 41

SP - 395

EP - 408

JO - Acta Veterinaria Hungarica

JF - Acta Veterinaria Hungarica

SN - 0236-6290

IS - 3-4

ER -