Thyrotropin and prolactin response to ambient temperature in newborn infants

F. Ruppert, E. Sulyok, F. Varga, I. F. Csaba, A. Petz

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Plasma TSH and PRL levels were measured by RIA in 8 full-term newborn infants with mean birth weight of 3420 g (range 3000-4100 g) and mean gestational age of 39.0 weeks (range 38-40 weeks) at postnatal age of 3-4 days. Determinations were performed at neutral thermal environment (32° C) and after 1 hr exposure to cold (28° C) and warm (37° C) environment. In response to cold challenge, TSH and PRL increased significantly from 4.17 ± 0.28 mU/l and 4625 ± mU/l to 4.76 ± 0.21 mU/l (p < 0.01) and 5975 ± 944 mU/l (p < 0.05), respectively. When the newborns were placed in warm environment, both TSH and PRL fell significantly to 3.52 ± 0.4 mU/l (p < 0.05) and 3318 ± 759 mU/l (p < 0.05), respectively. A weakly significant positive correlation was found between TSH and PRL levels suggesting that thermal stress in the newborn results in similar alterations in TSH and PRL, presumably through the same central mechanism.

Original languageEnglish
Pages (from-to)189-194
Number of pages6
JournalActa paediatrica Academiae Scientiarum Hungaricae
Issue number2
Publication statusPublished - Dec 1 1982

ASJC Scopus subject areas

  • Medicine(all)

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