Thrombotic thrombocytopenic purpura, moschcowitz syndrome

J. Müller, J. Czinyéri, I. Sasvári, M. Garami, G. Kovács

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was diagnosed. The adequate therapy was immediately started. TTP is quite a rare entity. The etiology and the pathogenesis are not well defined. The authors summarize the different pathomechanisms, which may play a role in the development of TTP. Similarity to the hemolytic uremic syndrome (HUS), therapeutic possibilities, prognosis and the outcome are also discussed. The importance of the early diagnosis of TTP in childhood, and life-saving effect of the adequate treatment are emphasized.

Original languageEnglish
Pages (from-to)144-149
Number of pages6
JournalInternational Pediatrics
Volume16
Issue number3
Publication statusPublished - 2001

Fingerprint

Thrombotic Thrombocytopenic Purpura
Hemolytic-Uremic Syndrome
Hyperbilirubinemia
Proteinuria
Thrombocytopenia
Anemia
Early Diagnosis
Therapeutics

Keywords

  • Plasma exchange (PEX)
  • Plasmapheresis
  • Thrombotic thrombocytopenic purpura (TTP)

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Müller, J., Czinyéri, J., Sasvári, I., Garami, M., & Kovács, G. (2001). Thrombotic thrombocytopenic purpura, moschcowitz syndrome. International Pediatrics, 16(3), 144-149.

Thrombotic thrombocytopenic purpura, moschcowitz syndrome. / Müller, J.; Czinyéri, J.; Sasvári, I.; Garami, M.; Kovács, G.

In: International Pediatrics, Vol. 16, No. 3, 2001, p. 144-149.

Research output: Contribution to journalArticle

Müller, J, Czinyéri, J, Sasvári, I, Garami, M & Kovács, G 2001, 'Thrombotic thrombocytopenic purpura, moschcowitz syndrome', International Pediatrics, vol. 16, no. 3, pp. 144-149.
Müller, J. ; Czinyéri, J. ; Sasvári, I. ; Garami, M. ; Kovács, G. / Thrombotic thrombocytopenic purpura, moschcowitz syndrome. In: International Pediatrics. 2001 ; Vol. 16, No. 3. pp. 144-149.
@article{e511197870f6427e8ca917a74a087796,
title = "Thrombotic thrombocytopenic purpura, moschcowitz syndrome",
abstract = "The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was diagnosed. The adequate therapy was immediately started. TTP is quite a rare entity. The etiology and the pathogenesis are not well defined. The authors summarize the different pathomechanisms, which may play a role in the development of TTP. Similarity to the hemolytic uremic syndrome (HUS), therapeutic possibilities, prognosis and the outcome are also discussed. The importance of the early diagnosis of TTP in childhood, and life-saving effect of the adequate treatment are emphasized.",
keywords = "Plasma exchange (PEX), Plasmapheresis, Thrombotic thrombocytopenic purpura (TTP)",
author = "J. M{\"u}ller and J. Cziny{\'e}ri and I. Sasv{\'a}ri and M. Garami and G. Kov{\'a}cs",
year = "2001",
language = "English",
volume = "16",
pages = "144--149",
journal = "International Pediatrics",
issn = "0885-6265",
publisher = "Miami Children's Hospital Medical Journal Inc.",
number = "3",

}

TY - JOUR

T1 - Thrombotic thrombocytopenic purpura, moschcowitz syndrome

AU - Müller, J.

AU - Czinyéri, J.

AU - Sasvári, I.

AU - Garami, M.

AU - Kovács, G.

PY - 2001

Y1 - 2001

N2 - The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was diagnosed. The adequate therapy was immediately started. TTP is quite a rare entity. The etiology and the pathogenesis are not well defined. The authors summarize the different pathomechanisms, which may play a role in the development of TTP. Similarity to the hemolytic uremic syndrome (HUS), therapeutic possibilities, prognosis and the outcome are also discussed. The importance of the early diagnosis of TTP in childhood, and life-saving effect of the adequate treatment are emphasized.

AB - The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was diagnosed. The adequate therapy was immediately started. TTP is quite a rare entity. The etiology and the pathogenesis are not well defined. The authors summarize the different pathomechanisms, which may play a role in the development of TTP. Similarity to the hemolytic uremic syndrome (HUS), therapeutic possibilities, prognosis and the outcome are also discussed. The importance of the early diagnosis of TTP in childhood, and life-saving effect of the adequate treatment are emphasized.

KW - Plasma exchange (PEX)

KW - Plasmapheresis

KW - Thrombotic thrombocytopenic purpura (TTP)

UR - http://www.scopus.com/inward/record.url?scp=0034834764&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034834764&partnerID=8YFLogxK

M3 - Article

VL - 16

SP - 144

EP - 149

JO - International Pediatrics

JF - International Pediatrics

SN - 0885-6265

IS - 3

ER -