Streptokinase-kezelést követö thrombotikus haemostasis-változások myocardiális infarctusban.

Translated title of the contribution: Thrombotic changes in hemostasis following streptokinase therapy in myocardial infarct

Research output: Contribution to journalReview article

Abstract

Thrombolytic treatment of acute myocardial infarction proved to be able to restore infarct artery patency and to decrease hospital mortality. The number of bleeding complications have remained at an acceptably low level, however some thromboembolic complications occurring during the first week following thrombolytic therapy have been recently observed. Signs of increased in vivo platelet activation (by measuring beta-thromboglobulin and thromboxane metabolite levels) and endothelial damage (Willebrand-factor estimations) could have been detected in our patients treated with brief high dose intravenous streptokinase, altogether with diminished antithrombin III and protein C antigen levels and activity. Intravenous streptokinase treatment of acute myocardial infarction might be able to cause thrombotic haemostatic alterations, which require meticulous haemostasis monitoring and early, correct antithrombiotic therapy.

Translated title of the contributionThrombotic changes in hemostasis following streptokinase therapy in myocardial infarct
Original languageHungarian
Pages (from-to)1691-1693
Number of pages3
JournalOrvosi hetilap
Volume131
Issue number31
Publication statusPublished - Aug 5 1990

ASJC Scopus subject areas

  • Medicine(all)

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