Three types of neurons in the medial cuneate nucleus of the cat

Genzoh Isomura, József Hámori

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A combined study utilizing Golgi-EM and γ-aminobutyrate (GABA) immunocytochemistry revealed the presence of 3 types of neurons in the cat medial cuneate nucleus. The 2 GABA-immunonegative neuron types were characterized by numerous and richly arborized dendritic processes; they were abundant in the rough endoplasmic reticulum and other cell organelles, and the perikarya were heavily covered by axosomatic terminal boutons. Their large neuron type (35 ± 3 μm diameter) exhibited thick and bifurcating dendrites, whereas the dendrites of the smaller (28 ± 3 μm) immunonegative nerve cell were more or less radially oriented. The third and smallest neuron type (24 ± 4 μm), shape not demonstrated by Golgi stain, indicated strong GABA-immunopositivity. The soma of this type had relatively little rough endoplasmic reticulum and other cell organelles, and received only few or slight axosomatic synapses, in contrast to the GABA-positive cells. A quantitative estimation of immunostained and immunonegative nerve cells in the 50 μm thick sections showed that 11-45% of nerve cells in the medial cuneate nucleus are GABA-positive.

Original languageEnglish
Pages (from-to)395-408
Number of pages14
JournalNeuroscience Research
Volume5
Issue number5
DOIs
Publication statusPublished - Jun 1988

Keywords

  • Cat
  • Fine structure
  • GABAergic neuron
  • Medial cuneate nucleus
  • Neuron type

ASJC Scopus subject areas

  • Neuroscience(all)

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