Three-dimensional photon radiotherapy planning for laryngeal and hypopharyngeal tumours

O. Ésik, W. Schlegel, J. Doll, G. Németh, W. J. Lorenz

Research output: Contribution to journalArticle

1 Citation (Scopus)


Three-dimensional absorbed dose distributions have been computed for high-energy photon radiation therapy of laryngeal and hypopharyngeal cancers, using a coaxial pair of opposing lateral beams in fixed positions. Treatment plans obtained under various conditions of irradiation are analyzed and compared for a cobalt-60 gamma unit (GAMMATRON S80, Siemens), photon beams from a 6 MV (CLINAC 1800, VARIAN), an 8 MV (SATURNE, CGR) and a 15 MV (MEVATRON 77, Siemens) linear accelerator. Using open fields a somewhat non-uniform and partly insufficient dose in target volume of interest is obtained with all treatment units if sufficient protection of the spinal cord is provided. The x-ray plans are somewhat superior to the cobalt-60 ones. Depending on the quantum energy and wedge isodose angle, wedging only slightly improves or sometimes moderately decreases the homogeneity of the dose in the target volume. According to these small and/or controversial effects of wedges their application seems unnecessary and/or non-convenient. Simulations show that extreme care is needed in positioning the isocentre: an accuracy of ± 3 mm is required in the median sagittal plane.

Original languageEnglish
Pages (from-to)439-446
Number of pages8
JournalActa Oncologica
Issue number4
Publication statusPublished - Jan 1 1990


  • 3-D
  • High-energy photons
  • Hypopharynx
  • Larynx
  • Open fields
  • Radiotherapy
  • Treatment planning
  • Wedging

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Radiology Nuclear Medicine and imaging

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