Thermoregulation of the rabbit during the late phase of endotoxin fever

Stanislav Vybíral, M. Székely, Ladislav Janský, Luděk Černý

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

In the late phase of the fever occurring 120 or more min after i.v. injection of endotoxin (1 ug/kg) to female rabbits, marked shifts of thresholds for respiratory evaporative heat loss and for peripheral vasodilatation to higher body core temperatures were observed. In contrast, the threshold body core temperature for cold thermogenesis was shifted downwards. As a result, the interthreshold zone was widened. Within the body temperature range of 37.4 to 39.9°C neither heat production or heat loss mechanisms were operant and the body temperature was determined mainly by passive heat transfer between the body and the environment. Outside this zone, the sensitivities of the heat and cold deference activities to changes in body core temperature appeared to be unchanged.

Original languageEnglish
Pages (from-to)220-222
Number of pages3
JournalPflugers Archiv European Journal of Physiology
Volume410
Issue number1-2
DOIs
Publication statusPublished - Sep 1987

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Body Temperature Regulation
Body Temperature
Endotoxins
Fever
Rabbits
Hot Temperature
Thermogenesis
Heat losses
Temperature
Vasodilation
Heat transfer
Injections

Keywords

  • Endotoxin fever
  • Rabbit
  • Thermoregulation

ASJC Scopus subject areas

  • Physiology

Cite this

Thermoregulation of the rabbit during the late phase of endotoxin fever. / Vybíral, Stanislav; Székely, M.; Janský, Ladislav; Černý, Luděk.

In: Pflugers Archiv European Journal of Physiology, Vol. 410, No. 1-2, 09.1987, p. 220-222.

Research output: Contribution to journalArticle

Vybíral, Stanislav ; Székely, M. ; Janský, Ladislav ; Černý, Luděk. / Thermoregulation of the rabbit during the late phase of endotoxin fever. In: Pflugers Archiv European Journal of Physiology. 1987 ; Vol. 410, No. 1-2. pp. 220-222.
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