The rapid progress in host-guest chemistry involving macrocycles has been due in no small part to the availability of reliable and extensive thermodynamic data for a large number of host-guest systems. Although valuable information can be derived from ΔH and ΔS values, few calorimetric data have been reported for host-guest systems. The procedures required to obtain reliable thermodynamic data are discussed and some of the kinds of information which these data can provide are given together with an example. Recent studies have demonstrated the power of combined thermodynamic and spectroscopic data in understanding host-guest interactions. Examples of these studies are presented.
ASJC Scopus subject areas
- Chemical Engineering(all)