Thermoanalytical behaviour of some coating free films

G. Regdon, A. Kósa, I. Erös, K. Pintye-Hódi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Differential scanning calorimetry (DSC) was used in the investigation of the behaviour of coating free films. The films were produced from two film-forming polymers which are chemically different but equally used for producing controlled-release dosage forms: Eudragit NE 30 D (synthetically produced polymethacrylate copolymer) and LustreClear product (mixture containing natural and semi-synthetic components: microcrystalline cellulose, hydroxy-ethyl cellulose, carrageenan and polyethylene glycol). During their comparative analysis the characteristic parameters of the DSC curves obtained with dynamic measurement method were used and their changes as a function of storage conditions and storage time were observed. It was found that the thermoanalytical behaviour of the examined methacrylate-based Eudragit NE and cellulose-based LustreClear films was different. The specific enthalpy change of Eudragit NE fresh films was very little, but it increased considerably during storage. The specific enthalpy change of LustreClear films was much greater but its value shows only a slight further increase during storage. The results obtained help to choose the proper temperature for coating and drying.

Original languageEnglish
Pages (from-to)793-797
Number of pages5
JournalJournal of Thermal Analysis and Calorimetry
Volume89
Issue number3
DOIs
Publication statusPublished - Sep 2007

Fingerprint

coatings
Coatings
cellulose
Cellulose
Differential scanning calorimetry
Enthalpy
heat measurement
enthalpy
scanning
Methacrylates
Carrageenan
Dosage Forms
drying
Polyethylene glycols
glycols
polyethylenes
copolymers
Drying
Polymers
Copolymers

Keywords

  • Carrageenan
  • DSC
  • Eudragit NE 30 D
  • Free films
  • LustreClear
  • Methacrylate copolymer
  • Microcrystalline cellulose
  • Storage conditions

ASJC Scopus subject areas

  • Chemical Engineering(all)

Cite this

Thermoanalytical behaviour of some coating free films. / Regdon, G.; Kósa, A.; Erös, I.; Pintye-Hódi, K.

In: Journal of Thermal Analysis and Calorimetry, Vol. 89, No. 3, 09.2007, p. 793-797.

Research output: Contribution to journalArticle

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