During the past year omeprazole-based triple therapies have achieved relatively low eradication rates, which lends support to the assertion that new regimens need to be developed. Other proton pump inhibitors (lansoprazole, pantoprazole, rabeprazole and esomeprazole) and ranitidine bismuth citrate have achieved results that are comparable to those of omeprazole. The optimal duration of eradication treatment (7-14 days) remains controversial. Second-line regimens, for use when eradication treatment with first-line regimens fails, have achieved high cumulative eradication rates. There is still a need for new compounds that are specific for Helicobacter pylori.
|Journal||Current Opinion in Gastroenterology|
|Issue number||SUPPL. 1|
|Publication status||Published - Dec 1 2001|
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