Rosszindulatú granulosasejt-daganatos betegek és gyógyulási eredményeik a Pécsi Nöi Klinikán.

Translated title of the contribution: Therapeutic results in patients with malignant granulosa cell tumors at the Gynecologic Clinic of the city of Pécs

K. Krommer, P. Göcze, Z. Garamvölgyi, K. Kovács, I. Szabó

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In the Department of Obstetrics and Gynecology, University Medical School of Pecs, Hungary 92 patients had been treated with malignant human granulosa cell tumor between 1960-1997. The youngest patient was 14 years old, the oldest 77. The average age was 52.5 years. The disease occurred mostly in 50-60 year old women, and most of them have never given birth before. In 64 cases (69%) metrorrhagia and low abdominal pain were the leading symptoms. 61% of cases the disease was diagnosed in the 1st stage, 14% in the 2nd, 18.5% in the 3rd, and 6.5% in the 4th stage. According to the endometrial histologic examination, data of increased estradiol production was found in 75% of the patients. Along with granulosa cell tumor breast cancer occurred in 2 cases, endometrial carcinoma was diagnosed in 4 cases, and atypical endometrial hyperplasia in 6 cases. After the operation 67 patients received radiation therapy, 5 chemotherapy and 16 combined radiation and chemotherapy. The 2 year survival rate of the 87 patients treated between 1960-1994 was 87.4% the 5 year survival rate was 64.4%. In the stage 1 had 92.4% of patients lived 2 years tumor free, 83.0% lived 5 years without recurrence of tumor. The cleaned 5 year survival rate was found in 88%. With the survey of the youngest patient's case the authors pointed out the highly malignant, rapid course, and the changing of the sera hormones during the therapy.

Original languageHungarian
Pages (from-to)1583-1586
Number of pages4
JournalOrvosi hetilap
Volume140
Issue number28
Publication statusPublished - Jul 11 1999

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Krommer, K., Göcze, P., Garamvölgyi, Z., Kovács, K., & Szabó, I. (1999). Rosszindulatú granulosasejt-daganatos betegek és gyógyulási eredményeik a Pécsi Nöi Klinikán. Orvosi hetilap, 140(28), 1583-1586.