The use of a new magnesium-derived hydride reagent for carbohydrate derivatives

G. Szabovik, A. Medgyes, Zs Antal, Zs Varga, W. Knott, A. Lipták

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The magnesium hydride based reagent in THF solution is an excellent tool for the stereoselective reduction of different uloside derivatives. Sugar azides, sulfonyl esters give aminosugars and methylose derivatives without affecting other functionalities. Halogenated sugars or methylene derivatives are stable under these conditions. The reagent can be applied in the presence of a wide variety of blocking groups (acetals, benzyl and allyl ethers, imides, C=C bonds) generally used in the carbohydrate chemistry.

Original languageEnglish
Pages (from-to)1003-1009
Number of pages7
JournalPolish Journal of Chemistry
Volume73
Issue number6
Publication statusPublished - Dec 1 1999

Keywords

  • Azides
  • Magnesium based hydride reagent
  • Reduction
  • Sulfonyl esters
  • Uloses

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'The use of a new magnesium-derived hydride reagent for carbohydrate derivatives'. Together they form a unique fingerprint.

  • Cite this

    Szabovik, G., Medgyes, A., Antal, Z., Varga, Z., Knott, W., & Lipták, A. (1999). The use of a new magnesium-derived hydride reagent for carbohydrate derivatives. Polish Journal of Chemistry, 73(6), 1003-1009.