The treatment of malignant scala posterior tumors in children

II. Preliminary result of the pre- and postoperative adjuvant chemotherapy of scala posterior tumors

D. Schuler, P. Somlo, R. Koos, R. Kalmanchey, E. Paraicz

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Ten children with posterior scala tumor infiltrating the surrounding brain substance and/or the brain stem entered in the present study with preoperative chemotherapy. In 8 of the 10 cases regression and necrosis of the tumor were seen by CT examination after the preoperative therapy. The diameter of the tumor decreased on the average by 35.6% (14.0-74.3%). The main side effect was granulocytopenia. According to our observation, the preoperative therapy enables a more radical surgery in some cases of medulloblastoma and ependymoma. Further observations are necessary to confirm these preliminary results.

Original languageEnglish
Pages (from-to)274-279
Number of pages6
JournalMedical and Pediatric Oncology
Volume21
Issue number4
Publication statusPublished - 1993

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Adjuvant Chemotherapy
Ependymoma
Neoplasms
Agranulocytosis
Medulloblastoma
Brain Stem
Necrosis
Therapeutics
Observation
Drug Therapy
Brain

Keywords

  • medulloblastoma
  • neutropenia
  • preoperative chemotherapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Pediatrics, Perinatology, and Child Health

Cite this

The treatment of malignant scala posterior tumors in children : II. Preliminary result of the pre- and postoperative adjuvant chemotherapy of scala posterior tumors. / Schuler, D.; Somlo, P.; Koos, R.; Kalmanchey, R.; Paraicz, E.

In: Medical and Pediatric Oncology, Vol. 21, No. 4, 1993, p. 274-279.

Research output: Contribution to journalArticle

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