The toxic megacolon is rare, life dangereous complication of the different forms of colitis diseases. It is a life threatening complication associated with acute dilatation and wall thickening of the colon as well as with a septic state. In the background of the syndrome inflammatory bowel diseases (ulcerative colitis, morbus Crohn) can be most frequently found. In the last years the toxic megacolon can be more frequently observed as a clinical complication of pseudomembraneous colitis and of inflammatory bowel diseases of infection origin (Clostridium difficile, Salmonella, Schigella, Yersinia, Campylobacter, Entamoeba, Cytomegalovirus). The authors review the incidence, aetiology and pathogenesis of the disease. The clinical symptomes and the diagnostic methods are discussed in details. The medical and surgical therapic modalities are summerized as well. The authors underline the multidisciplinarity in the treatment of toxic megacolon. Due to consensus with the patient a strict collaboration is required among the gastroenterologist, radiologist and the surgeons for the optimal timing of surgical intervention.
|Number of pages||6|
|Publication status||Published - Dec 1 2004|
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