The TMCrys server for supporting crystallization of transmembrane proteins

Julia K. Varga, Gábor E. Tusnády, Alfonso Valencia

Research output: Contribution to journalArticle

Abstract

Due to their special properties, the structures of transmembrane proteins are extremely hard to determine. Several methods exist to predict the propensity of successful completion of the structure determination process. However, available predictors incorporate data of any kind of proteins, hence they can hardly differentiate between crystallizable and non-crystallizable membrane proteins. Results: We implemented a web server to simplify running TMCrys prediction method that was developed specifically to separate crystallizable and non-crystallizable membrane proteins. Availability and implementation: http://tmcrys.enzim.ttk.mta.hu Supplementary information: Supplementary data are available at Bioinformatics online.

Original languageEnglish
Pages (from-to)4203-4204
Number of pages2
JournalBioinformatics
Volume35
Issue number20
DOIs
Publication statusPublished - Oct 15 2019

Fingerprint

Membrane Protein
Crystallization
Membrane Proteins
Servers
Server
Proteins
Protein
Web Server
Bioinformatics
Computational Biology
Differentiate
Completion
Predictors
Simplify
Availability
Membranes
Predict
Prediction

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

Cite this

The TMCrys server for supporting crystallization of transmembrane proteins. / Varga, Julia K.; Tusnády, Gábor E.; Valencia, Alfonso.

In: Bioinformatics, Vol. 35, No. 20, 15.10.2019, p. 4203-4204.

Research output: Contribution to journalArticle

Varga, Julia K. ; Tusnády, Gábor E. ; Valencia, Alfonso. / The TMCrys server for supporting crystallization of transmembrane proteins. In: Bioinformatics. 2019 ; Vol. 35, No. 20. pp. 4203-4204.
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