A metadoxin terápiás hatásának összehasonlítása alkoholos és nem alkoholos zsírmájban

Translated title of the contribution: The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis

László Váli, A. Blázovics, J. Fehér

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Alcohol-induced liver disease is one of the main epidemic problems of nowadays. Non-alcoholic steatohepatitis has been described only for some years, but it also needs much more attention in the future. The etiologic factors of both entities are quite different, but the patologic changes of the liver are nearly the same, therefore there could be certain drugs, that are equally effective in their therapy. Metadoxine is one of them, mainly because its protective effect against the damage done by free radicals. Metadoxine is a pyridoxine-pyrrolidone carboxylate with significant scavenging property. There are a lot of patients suffering from steatohepatitis, and they will face the complications of the liver damage. The aim is to provide better recovery and proper life quality, which is based on the deeper understanding of these mechanisms. Metadoxine is suitable for increasing reduced glutathion level, which is very important for the redox homeostasis of the liver and the whole body. The effectiveness of the drug is established both in acute and in chronic alcoholism, moreover it helps in staying abstinent.

Original languageHungarian
Pages (from-to)2409-2414
Number of pages6
JournalOrvosi Hetilap
Volume146
Issue number47
Publication statusPublished - 2005

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Therapeutic Uses
Fatty Liver
Liver
Pyrrolidinones
Pyridoxine
Pharmaceutical Preparations
Alcoholism
Oxidation-Reduction
Free Radicals
Glutathione
Liver Diseases
Homeostasis
Alcohols
Quality of Life
metadoxine
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A metadoxin terápiás hatásának összehasonlítása alkoholos és nem alkoholos zsírmájban. / Váli, László; Blázovics, A.; Fehér, J.

In: Orvosi Hetilap, Vol. 146, No. 47, 2005, p. 2409-2414.

Research output: Contribution to journalArticle

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