Abstract
Glucocorticoid hormones may have dual action on the stomach: physiological gastroprotective and pathological proulcerogenic one. In physiological conditions, even in acute stress situations, glucocorticoids have an adaptive effect on the stomach and, therefore, are gastroprotective. The findings that we review in this article suggest that glucocorticoids released during acute stress are naturally occurring protective factors that play an important role in maintenance of the gastric mucosal integrity.
| Original language | English |
|---|---|
| Pages (from-to) | 121-123 |
| Number of pages | 3 |
| Journal | Ideggyógyászati szemle |
| Volume | 67 |
| Issue number | 3-4 |
| Publication status | Published - Mar 3 2014 |
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Keywords
- Gastric erosion
- Gastroprotection
- Glucocorticoids
- Hans Selye
- Non-steroidal anti-inflammatory drugs
- Stress
- The hypothalamic-pituitary-adrenocortical axis
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
Cite this
The surprising dual action of glucocorticoids. / Filaretova, Ludmila; Makara, G.
In: Ideggyógyászati szemle, Vol. 67, No. 3-4, 03.03.2014, p. 121-123.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The surprising dual action of glucocorticoids
AU - Filaretova, Ludmila
AU - Makara, G.
PY - 2014/3/3
Y1 - 2014/3/3
N2 - Glucocorticoid hormones may have dual action on the stomach: physiological gastroprotective and pathological proulcerogenic one. In physiological conditions, even in acute stress situations, glucocorticoids have an adaptive effect on the stomach and, therefore, are gastroprotective. The findings that we review in this article suggest that glucocorticoids released during acute stress are naturally occurring protective factors that play an important role in maintenance of the gastric mucosal integrity.
AB - Glucocorticoid hormones may have dual action on the stomach: physiological gastroprotective and pathological proulcerogenic one. In physiological conditions, even in acute stress situations, glucocorticoids have an adaptive effect on the stomach and, therefore, are gastroprotective. The findings that we review in this article suggest that glucocorticoids released during acute stress are naturally occurring protective factors that play an important role in maintenance of the gastric mucosal integrity.
KW - Gastric erosion
KW - Gastroprotection
KW - Glucocorticoids
KW - Hans Selye
KW - Non-steroidal anti-inflammatory drugs
KW - Stress
KW - The hypothalamic-pituitary-adrenocortical axis
UR - http://www.scopus.com/inward/record.url?scp=84899829492&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84899829492&partnerID=8YFLogxK
M3 - Article
VL - 67
SP - 121
EP - 123
JO - Ideggyogyaszati Szemle
JF - Ideggyogyaszati Szemle
SN - 0019-1442
IS - 3-4
ER -