Abstract
Glucocorticoid hormones may have dual action on the stomach: physiological gastroprotective and pathological proulcerogenic one. In physiological conditions, even in acute stress situations, glucocorticoids have an adaptive effect on the stomach and, therefore, are gastroprotective. The findings that we review in this article suggest that glucocorticoids released during acute stress are naturally occurring protective factors that play an important role in maintenance of the gastric mucosal integrity.
| Original language | English |
|---|---|
| Pages (from-to) | 121-123 |
| Number of pages | 3 |
| Journal | Ideggyogyaszati szemle |
| Volume | 67 |
| Issue number | 3-4 |
| Publication status | Published - Mar 3 2014 |
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Keywords
- Gastric erosion
- Gastroprotection
- Glucocorticoids
- Hans Selye
- Non-steroidal anti-inflammatory drugs
- Stress
- The hypothalamic-pituitary-adrenocortical axis
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
Cite this
Filaretova, L., & Makara, G. (2014). The surprising dual action of glucocorticoids. Ideggyogyaszati szemle, 67(3-4), 121-123.