The study of spontaneous rosette forming in acute lymphocytic leukemia in infancy (Hungarian)

T. Revesz, R. Szigeti, D. Schuler

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The spontaneous rosette forming activity of 40 ALL and 32 control infants were studied. The peripheral lymphocytes of the control children bind in a median rate of 27.5% sheep red blood cells to their surface. The rosette forming activity of lymphoblasts of leukemic children is significantly decreased (median 4.6%). The number of rosette forming cells during intensive induction chemotherapy was much less than that of the controls (15.7%), while the lymphocytes of children in remission, obtaining maintenance therapy formed rosettes nearly in the normal rate (median 22.5%). The presence of sera obtained from leukemia patients before chemotherapy had no considerable effect on the rosette forming capacity of lymphocytes either of the controls or of the leukemic patients.

Original languageEnglish
Pages (from-to)259-262
Number of pages4
JournalMagyar onkologia
Issue number4
Publication statusPublished - Jan 1 1975


ASJC Scopus subject areas

  • Medicine(all)

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