The concentration of noradrenaline, dopamine and adrenaline was measured in 27 brain regions of adult spontaneously hypertensive rats (SH-rats) with established hypertension and normotensive Wistar/Kyoto rats (W/K-rats). Selectively elevated catecholamine levels were found in a restricted number of these regions from the SH-rats. Most differences (elevated noradrenaline) occurred in cell body regions of the medulla oblongata. In the A2 region of the NTS complex, increased levels of all three catecholamines were observed. In some supramedullary regions implicated in the control of blood pressure, elevated dopamine or adrenaline levels were found as well.
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