The sequential Sonogashira-click reaction: A versatile route to 4-aryl-1,2,3-triazoles

Krisztián Lörincz, Péter Kele, Zoltán Novák

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Aryl halides can be easily transformed in a one-pot procedure into 4-aryl-1,2,3-triazoles with palladium/copper-catalyzed Sonogashira-click reaction sequence, using trimethylsilylacetylene as acetylene surrogate.

Original languageEnglish
Pages (from-to)3527-3532
Number of pages6
JournalSynthesis
Issue number20
DOIs
Publication statusPublished - Dec 21 2009

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Keywords

  • Alkynes
  • Azides
  • Copper
  • Cross-coupling
  • Cycloadditions

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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