Az A-vitamin analóg- és származék-család jelentösége a sejtmüködés szabályozásában.

Translated title of the contribution: The role of vitamin A analogues and derivatives in the regulation of cell function

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The vitamin A and the retinoids, the vitamin A derivatives play an important role in the embryogenesis, in the modulation of the growth, in the differentiation of normal, premalignant and malignant epithelial and mesenchymal cells and in the maintenance of immune response. The effects of vitamin A are executed by two different mechanisms. While the carotenoids of provitamin A activity and the vitamin A--the retinol--itself are mainly antioxidant molecules and so some of their effects are partly similar to the effects of tocopherol, the retinoids, the derivatives of vitamin A, exert their diverse effects by regulating the expression of specific genes by the aid of specific nuclear receptors belonging to the family of steroid, thyroid hormone, and vitamin D3 receptors. The retinoids play a role in the modulation of the effect of these hormones as well.

Original languageHungarian
Pages (from-to)845-848
Number of pages4
JournalOrvosi Hetilap
Volume134
Issue number16
Publication statusPublished - Apr 18 1993

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Vitamin A
Retinoids
Calcitriol Receptors
Tocopherols
Carotenoids
Cytoplasmic and Nuclear Receptors
Thyroid Hormones
Embryonic Development
Antioxidants
Epithelial Cells
Steroids
Maintenance
Hormones
Gene Expression
Growth

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Az A-vitamin analóg- és származék-család jelentösége a sejtmüködés szabályozásában. / Vásárhelyi, B.; Blázovics, A.; Fehér, J.

In: Orvosi Hetilap, Vol. 134, No. 16, 18.04.1993, p. 845-848.

Research output: Contribution to journalArticle

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