The significance of nitric-oxide as a biological mediator is increasingly elucidated in various physiological processes. In addition to the endothelium dependent vasodilator effect it also plays an important role as a neurotransmitter. Possible synthesis of endothelial nitric-oxide is an essential factor in the regulation of blood pressure and utero-placental circulation. Recently the relationship of nitric-oxide and preeclampsia has extensively been studied. The results of human studies and animal experiments suggest that insufficient production of endothelial nitric-oxide probably has an important role in the pathomechanism of preeclampsia.
|Translated title of the contribution||The role of vascular nitric oxide (NO) in the pathomechanism of pre-eclampsia|
|Number of pages||5|
|Publication status||Published - Nov 19 1995|
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