A mikrobiom szerepe a fül-orr-gégészetben

Translated title of the contribution: The role of the microbiome in otorhinolaryngology

Szilvia Fekete, D. Szabó, László Tamás, Gábor Polony

Research output: Contribution to journalArticle

Abstract

Our health is highly determined by the diverse microbial community living within our body and upon our skin. Balance among the members of the commensal microbiota is essential for the preservation of health. New generation sequencing is a rapid, sensitive method for determining the whole microbiome without prior hypothesis and also gives information on the resistance and virulence status. Application of this method can help to identify the pathogens contributing to different diseases, and also the protective bacteria inhibiting their growth. Detecting the changes of the microbiome helps to identify new therapeutic targets and establish targeted antibiotic therapy. Broad-spectrum antibiotics also act against the beneficial members of the microbial flora, which may lead to the development of recurrent or chronic disease. Ear, nose and throat infections are the most common infective diseases in humans and the leading cause for antibiotic prescription worldwide. In recent years, many studies using molecular biology methods were performed examining the microbiome of healthy humans and in otorhinolaryngologic diseases. In the present work, the authors review the changes of the microbiological communities in the healthy state and in various pathologic states in the anatomic regions of the ear, nose and throat. Orv Hetil. 2019; 160(39): 1533-1541.

Original languageHungarian
Pages (from-to)1533-1541
Number of pages9
JournalOrvosi hetilap
Volume160
Issue number39
DOIs
Publication statusPublished - Sep 1 2019

Fingerprint

Microbiota
Otolaryngology
Anti-Bacterial Agents
Pharynx
Nose
Ear
Otorhinolaryngologic Diseases
Health
Prescriptions
Virulence
Molecular Biology
Chronic Disease
Bacteria
Skin
Therapeutics
Growth
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A mikrobiom szerepe a fül-orr-gégészetben. / Fekete, Szilvia; Szabó, D.; Tamás, László; Polony, Gábor.

In: Orvosi hetilap, Vol. 160, No. 39, 01.09.2019, p. 1533-1541.

Research output: Contribution to journalArticle

Fekete, S, Szabó, D, Tamás, L & Polony, G 2019, 'A mikrobiom szerepe a fül-orr-gégészetben', Orvosi hetilap, vol. 160, no. 39, pp. 1533-1541. https://doi.org/10.1556/650.2019.31451
Fekete, Szilvia ; Szabó, D. ; Tamás, László ; Polony, Gábor. / A mikrobiom szerepe a fül-orr-gégészetben. In: Orvosi hetilap. 2019 ; Vol. 160, No. 39. pp. 1533-1541.
@article{b243743e0f24471da5cd8f4c154d28a0,
title = "A mikrobiom szerepe a f{\"u}l-orr-g{\'e}g{\'e}szetben",
abstract = "Our health is highly determined by the diverse microbial community living within our body and upon our skin. Balance among the members of the commensal microbiota is essential for the preservation of health. New generation sequencing is a rapid, sensitive method for determining the whole microbiome without prior hypothesis and also gives information on the resistance and virulence status. Application of this method can help to identify the pathogens contributing to different diseases, and also the protective bacteria inhibiting their growth. Detecting the changes of the microbiome helps to identify new therapeutic targets and establish targeted antibiotic therapy. Broad-spectrum antibiotics also act against the beneficial members of the microbial flora, which may lead to the development of recurrent or chronic disease. Ear, nose and throat infections are the most common infective diseases in humans and the leading cause for antibiotic prescription worldwide. In recent years, many studies using molecular biology methods were performed examining the microbiome of healthy humans and in otorhinolaryngologic diseases. In the present work, the authors review the changes of the microbiological communities in the healthy state and in various pathologic states in the anatomic regions of the ear, nose and throat. Orv Hetil. 2019; 160(39): 1533-1541.",
keywords = "antibiotic, antibiotikum, garat, k{\"o}z{\'e}pf{\"u}l, microbiome, middle ear, mikrobiom, nasal cavity, orr{\"u}reg, pharynx",
author = "Szilvia Fekete and D. Szab{\'o} and L{\'a}szl{\'o} Tam{\'a}s and G{\'a}bor Polony",
year = "2019",
month = "9",
day = "1",
doi = "10.1556/650.2019.31451",
language = "Hungarian",
volume = "160",
pages = "1533--1541",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "39",

}

TY - JOUR

T1 - A mikrobiom szerepe a fül-orr-gégészetben

AU - Fekete, Szilvia

AU - Szabó, D.

AU - Tamás, László

AU - Polony, Gábor

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Our health is highly determined by the diverse microbial community living within our body and upon our skin. Balance among the members of the commensal microbiota is essential for the preservation of health. New generation sequencing is a rapid, sensitive method for determining the whole microbiome without prior hypothesis and also gives information on the resistance and virulence status. Application of this method can help to identify the pathogens contributing to different diseases, and also the protective bacteria inhibiting their growth. Detecting the changes of the microbiome helps to identify new therapeutic targets and establish targeted antibiotic therapy. Broad-spectrum antibiotics also act against the beneficial members of the microbial flora, which may lead to the development of recurrent or chronic disease. Ear, nose and throat infections are the most common infective diseases in humans and the leading cause for antibiotic prescription worldwide. In recent years, many studies using molecular biology methods were performed examining the microbiome of healthy humans and in otorhinolaryngologic diseases. In the present work, the authors review the changes of the microbiological communities in the healthy state and in various pathologic states in the anatomic regions of the ear, nose and throat. Orv Hetil. 2019; 160(39): 1533-1541.

AB - Our health is highly determined by the diverse microbial community living within our body and upon our skin. Balance among the members of the commensal microbiota is essential for the preservation of health. New generation sequencing is a rapid, sensitive method for determining the whole microbiome without prior hypothesis and also gives information on the resistance and virulence status. Application of this method can help to identify the pathogens contributing to different diseases, and also the protective bacteria inhibiting their growth. Detecting the changes of the microbiome helps to identify new therapeutic targets and establish targeted antibiotic therapy. Broad-spectrum antibiotics also act against the beneficial members of the microbial flora, which may lead to the development of recurrent or chronic disease. Ear, nose and throat infections are the most common infective diseases in humans and the leading cause for antibiotic prescription worldwide. In recent years, many studies using molecular biology methods were performed examining the microbiome of healthy humans and in otorhinolaryngologic diseases. In the present work, the authors review the changes of the microbiological communities in the healthy state and in various pathologic states in the anatomic regions of the ear, nose and throat. Orv Hetil. 2019; 160(39): 1533-1541.

KW - antibiotic

KW - antibiotikum

KW - garat

KW - középfül

KW - microbiome

KW - middle ear

KW - mikrobiom

KW - nasal cavity

KW - orrüreg

KW - pharynx

UR - http://www.scopus.com/inward/record.url?scp=85072576096&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85072576096&partnerID=8YFLogxK

U2 - 10.1556/650.2019.31451

DO - 10.1556/650.2019.31451

M3 - Article

C2 - 31544493

AN - SCOPUS:85072576096

VL - 160

SP - 1533

EP - 1541

JO - Orvosi Hetilap

JF - Orvosi Hetilap

SN - 0030-6002

IS - 39

ER -