Epidermalis növekedési faktor receptor család szerepe hámeredetu daganatok molekulárisan célzott gyógyszeres kezelésében és diagnosztiká jában

Translated title of the contribution: The role of the epidermal growth factor receptor family in the molecularly targeted therapy and diagnostics of epithelial malignancies

Várkondi Edit, Pintér Ferenc, I. Peták

Research output: Contribution to journalArticle

Abstract

Members of the EGFR (Epidermal Growth Factor Receptor) family proved to be remarkably important tumour therapeutic targets. Tumours are genetic disorders caused by mutations (amplification, pont mutation) affecting directly growth factor receptors and/or their downstream signalling proteins. Molecular diagnostics are essential for the personalized therapy with the new molecular-targeted drugs acting on the EGFR family.

Original languageHungarian
Pages (from-to)159-167
Number of pages9
JournalOrvoskepzes
Volume81
Issue number3
Publication statusPublished - 2006

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Epidermal Growth Factor Receptor
Mutation
Inborn Genetic Diseases
Growth Factor Receptors
Molecular Pathology
Neoplasms
Therapeutics
Pharmaceutical Preparations
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Epidermalis növekedési faktor receptor család szerepe hámeredetu daganatok molekulárisan célzott gyógyszeres kezelésében és diagnosztiká jában. / Edit, Várkondi; Ferenc, Pintér; Peták, I.

In: Orvoskepzes, Vol. 81, No. 3, 2006, p. 159-167.

Research output: Contribution to journalArticle

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