Epidermalis növekedési faktor receptor család szerepe hámeredetu daganatok molekulárisan célzott gyógyszeres kezelésében és diagnosztiká jában

Translated title of the contribution: The role of the epidermal growth factor receptor family in the molecularly targeted therapy and diagnostics of epithelial malignancies

Várkondi Edit, Pintér Ferenc, Peták István

Research output: Contribution to journalReview article

Abstract

Members of the EGFR (Epidermal Growth Factor Receptor) family proved to be remarkably important tumour therapeutic targets. Tumours are genetic disorders caused by mutations (amplification, pont mutation) affecting directly growth factor receptors and/or their downstream signalling proteins. Molecular diagnostics are essential for the personalized therapy with the new molecular-targeted drugs acting on the EGFR family.

Original languageHungarian
Pages (from-to)159-167
Number of pages9
JournalOrvoskepzes
Volume81
Issue number3
Publication statusPublished - Dec 1 2006

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ASJC Scopus subject areas

  • Medicine(all)

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