A prosztata specifikus antigén és a biopszia Gleason-score jelento″sége a prosztatarák helyi kiterjedetsé gének megítélésében, saját tapasztalataink alapján

Translated title of the contribution: The role of serum PSA level and Gleason score in the biopsy sample as predictors of local extension of the prostatic cancer in our material

Bérezi Csaba, Tóth György, Fiaskó Tibor, L. Muszbek, Z. Nemes, Tóth Csaba

Research output: Contribution to journalArticle

Abstract

The aim of the study was to evaluate factors which can predict the local stage in prostate cancer. 215 patients were involved in the study. In 176 patients, the tumour was organ confined (Group 1), in 39 patients (Group 2) the cancer showed extraprostatic extension. Preoperative computer tomography was performed in 165 cases. The authors analysed the relation between the preoperative concentration of prostate specific antigen (PSA), the Gleason score of the prostate biopsy and the extraprostatic infiltration of the tumour. The sensitivity of CT examination for periprostatic extension were 20.5%, respectively. The average preoperative serum level of PSA was 13.5 ng/ml in Group 1, and 23.1 ng/ml in Group 2 (p=0.0017). Histology showed extraprostatic extension of the tumor in 9.6% of the cases when the PSA was below 10 ng/ml. The average Gleason score of prostate biopsy specimen was 3.09 in Group 1, and it was 3.96 in Group 2 (p=0.0357). Extraprostatic spreading occurred in 18.4% of the cases when the Gleason score of the biopsy was

Original languageHungarian
Pages (from-to)137-142
Number of pages6
JournalMagyar Urologia
Volume16
Issue number3
Publication statusPublished - 2004

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Neoplasm Grading
Prostate-Specific Antigen
Prostatic Neoplasms
Biopsy
Serum
Prostate
Neoplasms
Histology
Tomography

ASJC Scopus subject areas

  • Urology

Cite this

A prosztata specifikus antigén és a biopszia Gleason-score jelento″sége a prosztatarák helyi kiterjedetsé gének megítélésében, saját tapasztalataink alapján. / Csaba, Bérezi; György, Tóth; Tibor, Fiaskó; Muszbek, L.; Nemes, Z.; Csaba, Tóth.

In: Magyar Urologia, Vol. 16, No. 3, 2004, p. 137-142.

Research output: Contribution to journalArticle

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abstract = "The aim of the study was to evaluate factors which can predict the local stage in prostate cancer. 215 patients were involved in the study. In 176 patients, the tumour was organ confined (Group 1), in 39 patients (Group 2) the cancer showed extraprostatic extension. Preoperative computer tomography was performed in 165 cases. The authors analysed the relation between the preoperative concentration of prostate specific antigen (PSA), the Gleason score of the prostate biopsy and the extraprostatic infiltration of the tumour. The sensitivity of CT examination for periprostatic extension were 20.5{\%}, respectively. The average preoperative serum level of PSA was 13.5 ng/ml in Group 1, and 23.1 ng/ml in Group 2 (p=0.0017). Histology showed extraprostatic extension of the tumor in 9.6{\%} of the cases when the PSA was below 10 ng/ml. The average Gleason score of prostate biopsy specimen was 3.09 in Group 1, and it was 3.96 in Group 2 (p=0.0357). Extraprostatic spreading occurred in 18.4{\%} of the cases when the Gleason score of the biopsy was",
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