The role of receptors of the plasma membrane and nuclear envelope in the failure of insulin imprinting in starving Tetrahymena.

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Starvation for 2 h does not disturb the insulin binding of Tetrahymena. At the same time imprinting does not develop at the first encounter with insulin and a down regulation is observed after 168 h. Starvation for 2 h reduces the insulin binding of the nucleus to the half value after starvation for 24 h and this change in binding becomes settled by 48 h. Imprinting is not elicited either in the nuclear membrane. The down-regulation can be observed also after 48 h but it is not present in the 168-h measurements. The experiments emphasize the increased sensitivity of binding sites of the nuclear envelope and the role of it in the development of imprinting.

Original languageEnglish
Pages (from-to)101-105
Number of pages5
JournalActa microbiologica Hungarica
Issue number2
Publication statusPublished - 1993


ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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