A PET-CT szerepe diffúz nagy B-sejtes limfómás betegek kezelésében

Translated title of the contribution: The role of PET/CT investigation in the management of patients with diffuse large B-cell lymphoma

Melinda Paksi, J. Demeter, Péter Szabó

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma (NHL). Although this lymphoma is curable, 40% of patients with DLBCL will die of relapsed or refractory disease. 18F-Fluoro-deoxyglucose positron emission tomography (FDG-PET) is a noninvasive, 3-dimensional, functional imaging modality. When combined with the anatomical imaging tool computed tomography (CT), PET/CT can differentiate among others necrotic masses and viable tumors. PET scan has become a basic clinical tool for staging and response assessment in aggressive lymphomas, such as DLBCL. It has been evaluated in pretreatment staging, restaging, monitoring during therapy, post-therapy surveillance and assessment of transformation. Based on the preliminary results of several studies FDG-PET scans play an important role in the early assessment of treatment response, in planning of the treatment including radiation therapy and in the estimation of prognosis.

Original languageHungarian
Pages (from-to)108-117
Number of pages10
JournalMagyar Onkologia
Volume60
Issue number2
Publication statusPublished - Jun 6 2016

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ASJC Scopus subject areas

  • Oncology

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