A PET helye az epilepsziás agyi múködészavar meghatározásában.

Translated title of the contribution: The role of PET scan in the investigation of epileptic functional disorders

Péter Halász, Magdolna Neuwirth, Pál Mikecz, Szabolcs Szakáll, Miklós Emri, Zsolt Zelei, Lajos Trón

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Systematic research is needed to evaluate the exact role of pathological factors in the determination of the extension of the hypometabolic area in partial epileptic patients. Together with structural damage, previous seizures, deafferentation and inhibitory mechanisms may contribute to the functional disorders. Benzodiazepine receptor studies showed that the density and binding ability of these receptors decreased in the area of epileptic functional disorder. Circumscribed hypermetabolism may appear during epileptic seizures or even more electrical discharges. The authors' PET studies aimed at presurgical evaluation showed that bilateral temporal hypometabolism occurred more frequently with right-sided seizure start. FDG-PET supported the localization of the pacemaker area both in temporal lobe epilepsies and in extratemporal epilepsies. This method proved instrumental in delineating the extension of the background pathology, too. The authors also demonstrated the strength of PET brain activation in mapping the hemispheric distribution of speech functions required in the planning of surgical interventions. The role of hippocampal sclerosis in temporal lobe hypometabolism was investigated and a short account is given of the observations relating to the relationship of hypermetabolism due to subclinical epileptic discharges and cognitive deficit symptoms.

Translated title of the contributionThe role of PET scan in the investigation of epileptic functional disorders
Original languageHungarian
Pages (from-to)1298-1301
Number of pages4
JournalOrvosi hetilap
Volume143
Issue number21 Suppl 3
Publication statusPublished - May 26 2002

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'The role of PET scan in the investigation of epileptic functional disorders'. Together they form a unique fingerprint.

  • Cite this