There is increasing evidence that cytokines play an important role in the pathogenesis of inflammatory skin diseases including psoriasis. In this review a summary of current knowledge is given on how the altered cytokine network is involved in the accumulation of inflammatory cells in lesional skin and in the epidermal hyperproliferation seen in psoriasis. The actions of the most important therapeutic compounds, such as corticosteroids, dithranol, cyclosporine, retinoids, vitamin D3 analogues and ultraviolet radiation, on the cytokine system are also discussed.
|Translated title of the contribution||The role of cytokines in the pathogenesis of psoriasis|
|Number of pages||6|
|Journal||Lege Artis Medicinae|
|Publication status||Published - May 20 1996|
ASJC Scopus subject areas