The role of alpha-adrenoreceptors in the treatment of urological diseases

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6 Citations (Scopus)

Abstract

One of the most important clinical pharmacological invention in the last decades the role of adrenoreceptors in urological disease. The disorders of emptying the bladder are associated to the urology. Plant extracts efficacy is low, indicated only in mild symptoms, surgery has to be performed in advanced cases. Recognise, discovering the role of adrenoreceptors in the prostate, bladder neck has changed the treatment of benign prostatic hyperplasia. Relieving the muscle tension leads to a better urinary flow, decreased residual urine and less complaints. Combination with 5α-reductase inhibitor a better results can be achieved. The inflammation in prostate is a frequent disease of all age of males. Spasm of the bladder neck maintains the complaints additional alpha-blocker treatment combined with antibiotics, anti-inflammatory drugs are the best choice to cure the patients. Alpha-adrenergic receptor can be found in the lower part of ureter as well. To promote the spontaneous expulsion of lower ureter stones, or fragments after ESWL (extracorporal shock wave lithotripsy) the alpha-blockers are highly recommended.

Original languageEnglish
Pages (from-to)328-331
Number of pages4
JournalNeurochemistry international
Volume51
Issue number5
DOIs
Publication statusPublished - Oct 1 2007

Keywords

  • Alpha-adrenoreceptor blocker
  • Benignus prostata hyperplasia
  • Prostatitis
  • Ureter stone

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Cell Biology

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