The release of kininase from rat isolated hearts during myocardial ischaemia

Maqsood Ahmad, Isaac J. Zeitlin, James R. Parratt

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

BK destroying activity was observed in rat isolated heart perfusates. BK was optimally degraded at pH 8.4 in rat heart. The results indicated that myocardial kinin degradation was due to ACE and a serine protease. These results suggest that bradykinin may have some cardioprotective role during myocardial ischaemia at acidic pH.

Original languageEnglish
Pages (from-to)299-300
Number of pages2
JournalImmunopharmacology
Volume33
Issue number1-3
DOIs
Publication statusPublished - Jun 1996

Keywords

  • bradykinin
  • kininase
  • myocardial ischaemia

ASJC Scopus subject areas

  • Pharmacology

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