The relationships of neukoendocrine tests in endogenous depression

Mihály Arató, Z. Ríhmer, Csaba M. Bánki, Paul Grof

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

1. 1. Amphetamine induced growth hormone (GH) response (Study 1) and TRH Induced TSH response (Study 2) were assessed in patients with endogenous depression (n = 20 and n = 22, respectively), who underwent a dexamethasone suppression test (DST) on the following day. 2. 2. The GH response to the amphetamine was significantly lower in the group of depressed patients than in the healthy controls (n = 13). 3. 3. There was no difference between the DST nonsuppressors (n = 12) and suppressors (n = 8) in the GH peak values. This data strongly suggests that the two tests are independent from each other. 4. 4. There was no significant relationship between the DST and TRH-TSH results. 5. 5. Patients with blunted TSH response to TRH have had significantly higher cerebrospinal fluid 5-HIAA levels.

Original languageEnglish
Pages (from-to)715-718
Number of pages4
JournalProgress in Neuro-Psychopharmacology and Biological Psychiatry
Volume7
Issue number4-6
DOIs
Publication statusPublished - 1983

Fingerprint

Depressive Disorder
Dexamethasone
Growth Hormone
Amphetamine
Hydroxyindoleacetic Acid
Cerebrospinal Fluid

Keywords

  • amphetamine-GH test
  • depression
  • dexamethasone suppression test
  • TRH-TSH test

ASJC Scopus subject areas

  • Biological Psychiatry
  • Pharmacology

Cite this

The relationships of neukoendocrine tests in endogenous depression. / Arató, Mihály; Ríhmer, Z.; Bánki, Csaba M.; Grof, Paul.

In: Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 7, No. 4-6, 1983, p. 715-718.

Research output: Contribution to journalArticle

Arató, Mihály ; Ríhmer, Z. ; Bánki, Csaba M. ; Grof, Paul. / The relationships of neukoendocrine tests in endogenous depression. In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 1983 ; Vol. 7, No. 4-6. pp. 715-718.
@article{2df96afa773a4c758fce54659edfff4c,
title = "The relationships of neukoendocrine tests in endogenous depression",
abstract = "1. 1. Amphetamine induced growth hormone (GH) response (Study 1) and TRH Induced TSH response (Study 2) were assessed in patients with endogenous depression (n = 20 and n = 22, respectively), who underwent a dexamethasone suppression test (DST) on the following day. 2. 2. The GH response to the amphetamine was significantly lower in the group of depressed patients than in the healthy controls (n = 13). 3. 3. There was no difference between the DST nonsuppressors (n = 12) and suppressors (n = 8) in the GH peak values. This data strongly suggests that the two tests are independent from each other. 4. 4. There was no significant relationship between the DST and TRH-TSH results. 5. 5. Patients with blunted TSH response to TRH have had significantly higher cerebrospinal fluid 5-HIAA levels.",
keywords = "amphetamine-GH test, depression, dexamethasone suppression test, TRH-TSH test",
author = "Mih{\'a}ly Arat{\'o} and Z. R{\'i}hmer and B{\'a}nki, {Csaba M.} and Paul Grof",
year = "1983",
doi = "10.1016/0278-5846(83)90051-9",
language = "English",
volume = "7",
pages = "715--718",
journal = "Progress in Neuro-Psychopharmacology and Biological Psychiatry",
issn = "0278-5846",
publisher = "Elsevier Inc.",
number = "4-6",

}

TY - JOUR

T1 - The relationships of neukoendocrine tests in endogenous depression

AU - Arató, Mihály

AU - Ríhmer, Z.

AU - Bánki, Csaba M.

AU - Grof, Paul

PY - 1983

Y1 - 1983

N2 - 1. 1. Amphetamine induced growth hormone (GH) response (Study 1) and TRH Induced TSH response (Study 2) were assessed in patients with endogenous depression (n = 20 and n = 22, respectively), who underwent a dexamethasone suppression test (DST) on the following day. 2. 2. The GH response to the amphetamine was significantly lower in the group of depressed patients than in the healthy controls (n = 13). 3. 3. There was no difference between the DST nonsuppressors (n = 12) and suppressors (n = 8) in the GH peak values. This data strongly suggests that the two tests are independent from each other. 4. 4. There was no significant relationship between the DST and TRH-TSH results. 5. 5. Patients with blunted TSH response to TRH have had significantly higher cerebrospinal fluid 5-HIAA levels.

AB - 1. 1. Amphetamine induced growth hormone (GH) response (Study 1) and TRH Induced TSH response (Study 2) were assessed in patients with endogenous depression (n = 20 and n = 22, respectively), who underwent a dexamethasone suppression test (DST) on the following day. 2. 2. The GH response to the amphetamine was significantly lower in the group of depressed patients than in the healthy controls (n = 13). 3. 3. There was no difference between the DST nonsuppressors (n = 12) and suppressors (n = 8) in the GH peak values. This data strongly suggests that the two tests are independent from each other. 4. 4. There was no significant relationship between the DST and TRH-TSH results. 5. 5. Patients with blunted TSH response to TRH have had significantly higher cerebrospinal fluid 5-HIAA levels.

KW - amphetamine-GH test

KW - depression

KW - dexamethasone suppression test

KW - TRH-TSH test

UR - http://www.scopus.com/inward/record.url?scp=0021051231&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021051231&partnerID=8YFLogxK

U2 - 10.1016/0278-5846(83)90051-9

DO - 10.1016/0278-5846(83)90051-9

M3 - Article

C2 - 6420844

AN - SCOPUS:0021051231

VL - 7

SP - 715

EP - 718

JO - Progress in Neuro-Psychopharmacology and Biological Psychiatry

JF - Progress in Neuro-Psychopharmacology and Biological Psychiatry

SN - 0278-5846

IS - 4-6

ER -