The relationship between serotypes and PFGE genotypes in isolates of Streptococcus pneumoniae from Hungary

O. Dobay, F. Rozgonyi, E. Hajdú, E. Nagy, M. Knausz, S. G.B. Amyes

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The relatedness of 112 penicillin-non-susceptible isolates of Streptococcus pneumoniae from Hungary was determined by pulsed-field gel electrophoresis (PFGE), serotyping and antibiotic susceptibility tests. The differences in PFGE patterns closely mirrored the changes in resistance. Some genotypes comprised multiple serotypes, and the genetic diversity among certain serotypes was considerable. Generally, serotyping alone was insufficient for epidemiological mapping of pneumococcal isolates. There was considerable serotype diversity, but the five most frequent international serotypes (6, 9, 14, 23, 19) were the most prevalent. In addition, the presence of some well-defined resistant international pneumococcal clones in the Hungarian population was identified.

Original languageEnglish
Pages (from-to)673-676
Number of pages4
JournalClinical Microbiology and Infection
Volume11
Issue number8
DOIs
Publication statusPublished - Aug 2005

Keywords

  • Genotypes
  • Hungary
  • Penicillin-non-susceptible
  • Pneumococci
  • Serotypes
  • Streptococcus pneumoniae

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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